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Record W4385349511 · doi:10.1002/lio2.1124

Treatment of sinus headache using a device that combines acoustic vibration with oscillating expiratory pressure

2023· article· en· W4385349511 on OpenAlexaboutno aff
Amar Miglani, Matthew Germroth, Kristina A. LaPointe, Shaun A. Nguyen, Ted A. Meyer

Bibliographic record

VenueLaryngoscope Investigative Otolaryngology · 2023
Typearticle
Languageen
FieldMedicine
TopicSinusitis and nasal conditions
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVisual analogue scaleAnesthesiaObservational studyAdverse effectMcGill Pain QuestionnairePhysical therapyInternal medicine

Abstract

fetched live from OpenAlex

Abstract Objective To determine if simultaneous administration of acoustic vibration and oscillating expiratory pressure affects the severity of facial pain among patients with complaint of “sinus headache”. Methods This is a prospective single‐arm observational study performed at a tertiary care medical center. Subjects with complaint of sinus headache without evidence of chronic rhinosinusitis on exam or computed tomography participated in a clinical study applying simultaneous acoustic vibrations and positive expiratory pressure to the nasal cavity twice daily over 4 weeks. Efficacy was assessed using three validated pain metrics—pain visual analog scale (VAS), brief pain inventory‐short form (BPI‐SF), and McGill pain questionnaire‐short form (MPQ‐SF). Device safety and patient satisfaction were also assessed using questionnaires. Results Twenty‐nine patients (mean age 49 years, 55% female) completed the study without any major adverse events. At the 4 week follow‐up, facial pain VAS improved from mean ± SD of 59.6 ± 15.7 to 34.6 ± 21.7 ( p < .001), BPI mean pain (mean ± standard deviation) improved from 4.4 ± 2.0 to 2.9 ± 1.9 ( p = .007), and MPQ‐SF total improved from 12.2 ± 6.5 to 6.5 ± 5.2 ( p < .001) with approximately 70% of patients achieving a minimal clinically important difference (MCID) across all metrics. Additionally, pain VAS was assessed 5 min after a single use at baseline with significant improvement ( p < .001). Eighty‐six percent of subjects would both use device again and recommend it to others. Conclusions Simultaneous administration of acoustic vibration and oscillating expiratory pressure appears to be a safe treatment for sinus headaches in patients without objective evidence of chronic sinusitis. Results from this initial study are promising with regard to efficacy in treatment of sinus headaches but will require further study. Level of evidence 2c.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.363
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.313
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

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