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Record W4385433515 · doi:10.14744/cm.2022.89266

Serum Macrophage Migration Inhibitory Factor Levels in the Patients with Active Ulcerative Colitis

2023· article· en· W4385433515 on OpenAlexaboutno aff
Enver Akbaş

Bibliographic record

VenueComprehensive Medicine · 2023
Typearticle
Languageen
FieldImmunology and Microbiology
TopicMacrophage Migration Inhibitory Factor
Canadian institutionsnot available
Fundersnot available
KeywordsMacrophage migration inhibitory factorUlcerative colitisMacrophageImmunologyInhibitory postsynaptic potentialMedicineInternal medicineChemistryCytokineDiseaseIn vitroBiochemistry

Abstract

fetched live from OpenAlex

Objective: Macrophage migration inhibitory factor (MIF) is a cytokine that plays a critical role in immunity and inflammation.We compared serum MIF levels in patients diagnosed with active ulcerative colitis (UC) for the 1 time with those in healthy controls and attempted to determine whether serum MIF levels were different in the patients with active UC. Materials and Methods:A total of 38 naive patients who were admitted to our hospital between 2019 and 2020 and diagnosed with active UC by colonoscopy were included in the study as the case group, and 37 patients without acute or chronic diseases whose colonoscopy was normal were included as the control group.Results: There was no statistically significant difference in MIF levels between the patients with UC and the control group (p>0.05).Serum MIF levels were analyzed by comparing the patients with UC and the control group in terms of disease localization and severity.The serum MIF levels of the patients with UC were grouped according to the Montreal classification (p>0.05) and the Truelove and Witts criteria.There was no statistically significant difference in serum MIF levels between the patient groups or between them and the control group (p>0.05).Conclusion: Serum MIF levels were not higher in the patients with naive active US than in healthy control subjects.There are not many previous clinical studies on this topic.Further clinical studies are needed to investigate serum MIF levels in UC.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.268
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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