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Record W4385477002 · doi:10.1002/cyto.a.24776

<scp>flowSim</scp> : Near duplicate detection for flow cytometry data

2023· article· en· W4385477002 on OpenAlexafffund
Sebastiano Montante, Yixuan Chen, Ryan R. Brinkman

Bibliographic record

VenueCytometry Part A · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSingle-cell and spatial transcriptomics
Canadian institutionsUniversity of British ColumbiaTerry Fox Research Institute
FundersNational Institute of Biomedical Imaging and BioengineeringNational Institute of Allergy and Infectious DiseasesNatural Sciences and Engineering Research Council of CanadaNational Institutes of Health
KeywordsOverfittingComputer scienceCluster analysisBivariate analysisRedundancy (engineering)Data miningPattern recognition (psychology)Artificial intelligencePreprocessorMachine learningArtificial neural network

Abstract

fetched live from OpenAlex

The analysis of large amounts of data is important for the development of machine learning (ML) models. flowSim is the first algorithm designed to visualize, detect and remove highly redundant information in flow cytometry (FCM) training sets to decrease the computational time for training and increase the performance of ML algorithms by reducing overfitting. flowSim performs near duplicate image detection by combining community detection algorithms with the density analysis of the marker expression values. flowSim clustering compared to consensus manual clustering on a dataset composed of 160 images of bivariate FCM data had a mean Adjusted Rand Index of 0.90, demonstrating its efficiency in identifying similar patterns. flowSim selectively discarded near duplicate files in datasets constructed with known redundancy, and removed 92.6% of FCM images in a dataset of over 500,000 drawn from public repositories.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.053
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Software · Consensus signal: Software
Teacher disagreement score0.170
Threshold uncertainty score0.569

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.053
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0080.010
Science and technology studies0.0030.002
Scholarly communication0.0040.004
Open science0.0080.004
Research integrity0.0030.005
Insufficient payload (model declined to judge)0.1700.067

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.292
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes2
Has abstractyes

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