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Are commercial soy-sauce products naturally gluten-free? Preliminary evaluation of selected products sold in the USA

2023· article· en· W4385686904 on OpenAlexaboutno aff
SHAMBHAVI DEVARAHALLI SHIVARAMAIAH, Yash Shah, Rick Jorgensen, Venugopal Gangur

Bibliographic record

VenueThe Journal of Immunology · 2023
Typearticle
Languageen
FieldMedicine
TopicCeliac Disease Research and Management
Canadian institutionsnot available
Fundersnot available
KeywordsGlutenFood scienceIngredientGluten freeWheat allergyChemistryFood allergyBiologyAllergy

Abstract

fetched live from OpenAlex

Abstract Gluten present in wheat, rye, and barley has been linked to 3 types of immune mediated disorders: Celiac disease, non-celiac gluten sensitivity and wheat hypersensitivity (or wheat allergy). Consequently, detection of gluten in food products is routinely used to validate gluten-free products meant for gluten-sensitive subjects. Fermentation processing has been shown to be effective in degrading food allergens including gluten. Most commercial soy sauce products (SSPs) use wheat in addition to soybean as a major ingredient in their production, thus presence of wheat gluten is expected in such products. Here we tested the hypothesis that commercial SSPs sold in the retail market in the USA will test positive for gluten independent of the country of origin. Commercial SSPs were tested for gluten presence using gluten test kit (LOD, 5 ppm). The test kit was validated for positivity using purified gluten extracted from durum wheat flour and for negativity by screening 2 commercial gluten-free SSPs. The following products have been tested: 4 products from China, 3 from USA, 1 from Canada and Taiwan respectively. Commercial SSPs when used without dilution in the food extract buffer rendered the test kit system invalid for testing. Therefore, a dilution of 1/10 was used in testing. Despite identifying wheat as an ingredient on the product label, all SSPs from USA, Canada, and Taiwan tested negative for gluten. Among these products, only 1 from china tested slightly positive for gluten. These results demonstrate that most commercial SSPs sold in the united states, independent of country of origin, used in this study test negative for the gluten content despite identifying wheat as a major ingredient on the labels. Further product screening is in progress. USDA/NIFA

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.338
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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