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Record W4385878712 · doi:10.1101/2023.08.12.23294029

Comparisons of Auditory Steady State and Auditory Brainstem Response Thresholds in Infants with Normal Hearing and Conductive Hearing Loss

2023· preprint· en· W4385878712 on OpenAlexafffund
Hope Valeriote, Susan A. Small

Bibliographic record

VenuemedRxiv · 2023
Typepreprint
Languageen
FieldNeuroscience
TopicHearing, Cochlea, Tinnitus, Genetics
Canadian institutionsGlenrose Rehabilitation HospitalUniversity of British ColumbiaAlberta Health Services
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of British ColumbiaUniversity of Saskatchewan
KeywordsAudiologyConductive hearing lossHearing lossBone conductionAuditory brainstem responseSteady state (chemistry)MedicineChemistry

Abstract

fetched live from OpenAlex

ABSTRACT This study investigates how well the air- and bone-conduction auditory steady-state response detects mild conductive hearing loss compared to the auditory brainstem response in young infants. Air-bone gap sizes are compared between infants with normal hearing and conductive loss using a two-group cross-sectional design. Twenty-three (500 Hz) and 22 (2000 Hz) infants (0-6 months of age) with normal hearing and 15 (500 Hz) infants with conductive loss were recruited from newborn hearing screening. Thresholds were obtained to frequency-specific air- and bone-conducted stimuli. There were no instances of conductive loss at 2000 Hz. 500 Hz mean thresholds and air-bone gap sizes were compared. Sensitivity and specificity for identifying conductive loss were measured. Overall, mean bone-conduction thresholds were similar between groups, and mean 500-Hz air conduction thresholds were higher with larger air-bone gap size for infants with conductive loss. Sensitivity and specificity for identifying conductive loss was highest for air-conduction auditory brainstem response threshold measurement compared to screening and auditory steady-state response threshold measurements. Compared to the auditory brainstem response, the variability of auditory steady-state response thresholds and air-bone gap size was too great to reliably separate normal hearing from mild conductive loss. More research is needed using infants with varying degrees of hearing loss at multiple frequencies to fully assess the appropriateness of the auditory steady-state response as a clinical diagnostic tool for an infant population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.314
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2023
Admission routes2
Has abstractyes

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