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Record W4386325006 · doi:10.1093/pch/pxad060

Failure to thrive and hypercalcemia in a 5-month-old male

2023· article· en· W4386325006 on OpenAlexaffabout
Maggie McNeill, Zoya Thawer, Manpreet Doulla

Bibliographic record

VenuePaediatrics & Child Health · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA regulation and disease
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsFailure to thriveMedicinePsychologyPediatrics

Abstract

fetched live from OpenAlex

A previously healthy, unvaccinated 5-month-old male presented to a rural emergency department with a 2-month history of progressive constipation, cough, decreased oral intake, and poor weight gain. His physical examination revealed an alert baby with a sunken fontanelle, a distended abdomen with no organomegaly, and a weight decrease from the 85th percentile to the 10th percentile over 2 months. He was not on any medications or supplements, but he had been on Vitamin D previously which his mother administered for his cough. Pregnancy, delivery, and family history were unremarkable. Given the cough, the patient was sent home with 10 days of amoxicillin and 10 days of prednisolone. Though the cough resolved, the other symptoms did not, leading to his re-presentation and further investigations. Bloodwork revealed a normal complete blood count, creatinine, glucose, urea, C-reactive protein, TSH, cortisol, and albumin levels. Electrolyte panel reported a normal sodium and potassium, but an elevated total of 3.97 mmol/L (ref 2.20 to 2.80 mmol/L), ionized calcium of 2.11 mmol/L (ref 1.09 to 1.25 mmol/L), a low phosphate of 0.89 mmol/L (ref 1.2 to 2.2 mmol/L) and an appropriately suppressed PTH of 0.4 mmol/L (ref 1.4 to 6.8 mmol/L).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.035

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.260
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

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