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Tertiary lymphoid structures and B cells: An intratumoral immunity cycle

2023· review· en· 284 citations· W4386608057 on OpenAlex· 10.1016/j.immuni.2023.08.009

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
Meta-epidemiology (narrow)
Consensus categories
none
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Other designConsensus signal: none
Genre
Candidate signal: ReviewConsensus signal: Review
Teacher disagreement score
0.986
Threshold uncertainty score
1.000
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.049
GPT teacher head0.352
Teacher spread
0.303 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Immunity
Topic
Cancer Immunotherapy and Biomarkers
Field
Medicine
Canadian institutions
not available
Funders
Sorbonne UniversitéInstitute of Cancer ResearchInstitut National Du CancerLigue Contre le CancerInstitut National de la Santé et de la Recherche MédicaleFondation ARC pour la Recherche sur le CancerAgence Nationale de la RechercheUniversité de ParisAssociation pour la Recherche sur le Cancer
Keywords
BiologyFollicular dendritic cellsImmunityAntibodyImmunologyContext (archaeology)Immune systemAntigenAffinity maturationAntigen presentationLymphatic systemCancer researchAntigen-presenting cellT cell
Has abstract in OpenAlex
no