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Record W4386656961 · doi:10.1093/eurpub/ckab165.294

Survey of Public Health Professionals on perspectives towards Direct-to-Consumer Genetic Tests

2021· article· en· W4386656961 on OpenAlexaff
Michele Sassano, Ilda Hoxhaj, Jovana Stojanovic, Anna Acampora, Stefania Boccia

Bibliographic record

VenueEuropean Journal of Public Health · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsConcordia UniversityCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
Fundersnot available
KeywordsPublic healthHealth professionalsMedicineFocus groupHealth careFamily medicinePsychologyNursingPolitical scienceMarketingBusiness

Abstract

fetched live from OpenAlex

Abstract Background The diffusion of Direct-to-Consumer Genetic Tests (DTC-GTs) requires properly literate professionals to appropriately address the challenges they pose to Public Health (PH). Hence, we conducted a survey to assess the current state of knowledge, attitudes, and behaviors of PH professionals members of the European Public Health Association (EUPHA) towards DTC-GTs. Methods The results of a scoping review conducted on PubMed to identify articles on healthcare professionals' perspectives towards DTC-GTs were used to elaborate a survey, which was validated through a focus group with experts. EUPHA members were invited to participate through email invitation, and EUPHA and EUPHAnxt newsletters. We performed a descriptive analysis of the results, and a univariate analysis to evaluate associations between selected variables. Results Two hundred and seventy-seven PH professionals (44.4% male, 55.6% female) completed the survey, 67.1% of whom were not involved in genetics or genomics within their professional activities. Although 78.0% were that companies are advertising and selling genetic tests directly to consumers, most of them reported a low level of awareness towards DTC-GTs applications and regulation aspects. The majority reported that a qualified health professional be involved in the DTC-GT process (91.7%), and did not feel prepared to address citizens' questions (64.6%). Eventually, 72.6% of the respondents stated that the provision of DTC-GT should be regulated on a national level, similarly to medicines. Conclusions Our results revealed a high level of awareness about the existence of DTC-GTs. Despite the overall positive attitudes, PH professionals reported a high need for strengthening regulatory aspects of DTC-GTs provision process. The growing interest of DTC-GTs among citizens and the poor knowledge of PH Professionals about these tests highlights the need to identify strategies for literacy improvement. Key messages Given the challenges for health systems, improving Public Health professionals' literacy on new technologies such as Direct-to-Consumer Genetic Tests is essential. The need for strengthening the regulation of Direct-to-Consumer Genetic Tests expressed Public Health professionals should guide policymakers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.043
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.062

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.043
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.376
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2021
Admission routes1
Has abstractyes

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