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Record W4386697668 · doi:10.1021/acs.jchemed.3c00220

Geiger Mode Single Photon Counting: A Laboratory Experiment Exploring Delayed Fluorescence in Plants

2023· article· en· W4386697668 on OpenAlexafffund
Christopher W. Schruder, Christopher J. Barrett, William J. Pietro, Ozzy Mermut

Bibliographic record

VenueJournal of Chemical Education · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced Fluorescence Microscopy Techniques
Canadian institutionsMcGill UniversityYork University
FundersNatural Sciences and Engineering Research Council of CanadaCanada First Research Excellence FundCanada Foundation for InnovationYork University
KeywordsPhotomultiplierPhotonicsSilicon photomultiplierPhoton countingNanotechnologyOptoelectronicsPhotonEngineering physicsLight intensityDetectorPhysicsComputer scienceOpticsMaterials scienceScintillator

Abstract

fetched live from OpenAlex

The time-resolved detection of very low intensity light emission has become an essential capability in many areas of science including molecular biology, fluorimetry, DNA sequencing, virus detection, nanoparticle research, and optical materials development. Among the most basic techniques for the detection of rapidly fluctuating low-intensity light is photon counting. Despite its extensive applications in the physical and biological sciences and engineering, photon counting techniques have traditionally been left out of undergraduate curricula due to the prohibitive cost of the equipment and the complexity of its operation. However, the recent development of the low-cost silicon photomultiplier device, a solid-state single photon avalanche diode detector, has enabled the availability of easy-to-operate, low voltage, advanced timing performance, and highly sensitive photon counting systems well within the budget of undergraduate teaching laboratories. In this contribution, we provide a strategy to introduce undergraduate interdisciplinary chemistry and physics students to silicon-photomultiplier-based photon counting through the interesting phenomenon of delayed fluorescence from photosystem II in plants. This experiment is perhaps best suited for an upper-level undergraduate laboratory and should stimulate the interest of students across a wide variety of disciplines, from physical chemistry to molecular biophysics to photonics instrumental analysis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.319
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes2
Has abstractyes

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