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Record W4387030598 · doi:10.48550/arxiv.2309.12325

FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare

2023· preprint· en· W4387030598 on OpenAlexfundno aff
Karim Lekadir, Aasa Feragen, Abdul Joseph Fofanah, Alejandro F. Frangi, Alena Buyx, Anais Emelie, Andrea Lara, Antonio R. Porras, An‐Wen Chan, Arcadi Navarro, Ben Glocker, Benard Ohene Botwe, Bishesh Khanal, Brigit Beger, Carol C. Wu, Celia Cintas, Curtis P. Langlotz, Daniel Rueckert, Deogratias Mzurikwao, Dimitrios I. Fotiadis, Doszhan Zhussupov, Enzo Ferrante, Erik Meijering, Eva Weicken, Fabio A. González, Folkert W. Asselbergs, Fred Prior, Gabriël P. Krestin, Gary Collins, Geletaw Sahle Tegenaw, Georgios Kaissis, Gianluca Misuraca, Gianna Tsakou, Girish Dwivedi, Haridimos Kondylakis, Harsha Jayakody, Henry C Woodruf, Hugo J.W.L. Aerts, Ian Walsh, Ioanna Chouvarda, Irène Buvat, Islem Rekik, James S. Duncan, Jayashree Kalpathy-Cramer, Jihad Zahir, Jinah Park, John Mongan, Judy Wawira Gichoya, Julia A. Schnabel, Kaisar Kushibar, Katrine Riklund, Kensaku Mori, Kostas Marias, Lameck Mbangula Amugongo, Lauren A. Fromont, Lena Maier‐Hein, L. Cerdá Alberich, Letícia Rittner, Lighton Phiri, Linda Marrakchi‐Kacem, Lluís Donoso-Bach, Luis Martí‐Bonmatí, M. Jorge Cardoso, Maciej Bobowicz, Mahsa Shabani, Manolis Tsiknakis, María A. Zuluaga, Mária Bieliková, Marie-Christine Fritzsche, Marius George Linguraru, Markus Wenzel, Marleen de Bruijne, Martin G. Tolsgaard, Marzyeh Ghassemi, Md. Ashrafuzzaman, Melanie Goisauf, Mohammad Yaqub, Mónica Cano Abadía, Mukhtar M. E. Mahmoud, Mustafa Elattar, Nicola Rieke, Nickolas Papanikolaou, Noussair Lazrak, Oliver Díaz, Olivier Salvado, Oriol Pujol, Ousmane Sall, Pamela Guevara, Peter Gordebeke, Philippe Lambin, Pieta Brown, Purang Abolmaesumi, Qi Dou, Qinghua Lu, Richard Osuala, Rose Nakasi, S Kevin Zhou, Sandy Napel, Sara Colantonio, Shadi Albarqouni, Smriti Joshi, Stacy M. Carter, Stefan Klein, Steffen E. Petersen, Susanna Aussó, Suyash Awate, Tammy Riklin Raviv, Tessa S. Cook, Tinashe Mutsvangwa, Wendy Rogers, Wiro J. Niessen, Xénia Puig-Bosch, Yi Zeng, Yunusa Garba Mohammed, Yves Saint James Aquino, Zohaib Salahuddin, Martijn P. A. Starmans

Bibliographic record

VenuearXiv (Cornell University) · 2023
Typepreprint
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsnot available
FundersNational Institute of Biomedical Imaging and BioengineeringFogarty International CenterNatural Sciences and Engineering Research Council of CanadaInstitute for Information and Communications Technology PromotionInstituto de Salud Carlos IIIMedical Research CouncilCentre National de la Recherche ScientifiqueCancer Research UKKWF KankerbestrijdingConselho Nacional de Desenvolvimento Científico e TecnológicoNational Natural Science Foundation of ChinaHORIZON EUROPE Framework ProgrammeNederlandse Organisatie voor Wetenschappelijk OnderzoekAgence Nationale de la RechercheAgencia Nacional de Investigación y DesarrolloAgency for Science, Technology and ResearchNational Health and Medical Research CouncilMinistério da Ciência, Tecnologia e InovaçãoEuropean Regional Development FundU.S. Department of DefenseEuropean CommissionNational Institutes of HealthRoyal Academy of EngineeringNational Institute for Health and Care ResearchGordon and Betty Moore Foundation
KeywordsSoftware deploymentHealth careApplications of artificial intelligenceBest practiceEngineering ethicsComputer scienceKnowledge managementArtificial intelligenceEngineeringPolitical scienceSoftware engineering

Abstract

fetched live from OpenAlex

Despite major advances in artificial intelligence (AI) for medicine and healthcare, the deployment and adoption of AI technologies remain limited in real-world clinical practice. In recent years, concerns have been raised about the technical, clinical, ethical and legal risks associated with medical AI. To increase real world adoption, it is essential that medical AI tools are trusted and accepted by patients, clinicians, health organisations and authorities. This work describes the FUTURE-AI guideline as the first international consensus framework for guiding the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI consortium was founded in 2021 and currently comprises 118 inter-disciplinary experts from 51 countries representing all continents, including AI scientists, clinicians, ethicists, and social scientists. Over a two-year period, the consortium defined guiding principles and best practices for trustworthy AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. The FUTURE-AI framework was established based on 6 guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 28 best practices were defined, addressing technical, clinical, legal and socio-ethical dimensions. The recommendations cover the entire lifecycle of medical AI, from design, development and validation to regulation, deployment, and monitoring. FUTURE-AI is a risk-informed, assumption-free guideline which provides a structured approach for constructing medical AI tools that will be trusted, deployed and adopted in real-world practice. Researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of medical AI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.188
metaresearch head score (Gemma)0.206
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.188
Threshold uncertainty score0.993

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1880.206
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0050.013
Bibliometrics0.0160.011
Science and technology studies0.0050.009
Scholarly communication0.0140.013
Open science0.0180.020
Research integrity0.0300.024
Insufficient payload (model declined to judge)0.0050.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.313
GPT teacher head0.357
Teacher spread0.044 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2023
Admission routes1
Has abstractyes

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