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Record W4387260451 · doi:10.1002/uog.27116

EP26.01: Imaging review of five cases of uterine PEComas

2023· article· en· W4387260451 on OpenAlexaff
Seng Thipphavong

Bibliographic record

VenueUltrasound in Obstetrics and Gynecology · 2023
Typearticle
Languageen
FieldMedicine
TopicTuberous Sclerosis Complex Research
Canadian institutionsWomen's College Hospital
Fundersnot available
KeywordsMedicineHistopathologyUterine fibroidsPathologyUterusMagnetic resonance imagingLeiomyomaRadiologyUterine leiomyomaInternal medicine

Abstract

fetched live from OpenAlex

1. To become familiar with the entity of uterine PEComa, along with the ultrasound and correlative MRI appearances of uterine PEComa. 2. To understand the importance of histopathology and immunohistochemistry in the diagnosis of PEComa. 3. To learn about the management of uterine PEComa. 1. Presentation of a series of pathology-proven uterine PEComas, with a focus on initial ultrasound imaging appearances and correlative appearance on MRI. 2. Review the distinctive histopathology and immunohistochemistry of PEComas. 3. Discussion on the management of uterine PEComas. A series of 5 pathology-proven uterine PEComas were reviewed, with patient age ranging from 29 to 80 years old. Uterine PEComas on ultrasound most often presented as a large solid uterine mass ranging in size from 2.5 to 13.0 cm and were mistakenly diagnosed as uterine fibroids (80%). One mass was misdiagnosed as a mesenteric GIST. Pathology showed malignant features of increased mitotic activity, necrosis, and marked atypia in 60% of cases. On MRI, all masses demonstrated intermediate T2-signal intensity, 40% hemorrhage, and 60% cystic/necrotic change. Uterine PEComas often present as a large uterine mass on ultrasound and can have a varied appearance mimicking that of uterine fibroids or uterine sarcomas. A prospective diagnosis of PEComa can be included when a growing uterine mass is identified, with atypical features of a fibroid and corresponding intermediate T2-signal intensity is seen on MRI (i.e. T2 signal higher than that of a typical fibroid or skeletal muscle). Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.059
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.180
Threshold uncertainty score0.949

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.059
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.339
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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