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Record W4387310080 · doi:10.21203/rs.3.rs-3372430/v1

The RESTORE C19 Study: Outcomes for women denied immediate breast reconstruction in the United Kingdom during the first wave of the COVID-19 pandemic.

2023· preprint· en· W4387310080 on OpenAlexaff
Katherine Fairhurst, Rajiv Dave, Rachel O’Connell, Raghaven Vidya, Patricia Fairbrother, J Skillman, Leila Rooshenas, Shelley Potter

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicBreast Implant and Reconstruction
Canadian institutionsRoyal Ottawa Mental Health Centre
FundersElizabeth Blackwell Institute for Health Research, University of BristolUniversity of BristolNational Institute for Health and Care Research
KeywordsPandemicCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyHistoryInternal medicineDiseaseOutbreakInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

Abstract Purpose The RESTORE C19 study aimed to explore outcomes for women not offered immediate breast reconstruction (IBR) following mastectomy for breast cancer during the first wave of the COVID-19 pandemic in the UK. Methods Women who were not offered IBR during the first wave of the COVID-19 pandemic (March-October 2020) were identified from the B-Map-C study database. Local collaborators were contacted between December 2021 and July 2022 to provide follow up data on the cohort, specifically whether women had been seen to discuss delayed breast reconstruction (DBR) and if so by whom; the receipt and timing of delayed reconstruction or documented decisions not to pursue reconstruction. Results Of the 366 women who were not offered IBR, complete follow-up data were available for 311 (85.0%). At a time point of between 21–28 months after mastectomy, less than half of women (n = 149, 47.6%) had been seen by a surgeon to discuss DBR and less than a third (n = 91, 29.2%) had been referred to plastic surgery to discuss autologous options. Only 21 (6.8%) women had actually received a DBR (4 with implant, 17 with autologous tissue). Almost one in five (n = 57) had decided against reconstructive surgery. Conclusions The majority of women denied IBR during the first wave of COVID-19 are still waiting for reconstructive surgery with almost 20% deciding not to pursue this option. Qualitative work is now needed to explore the experiences of this group in more detail to determine how best to support these women to complete their breast cancer journeys.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score0.141

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.201
GPT teacher head0.417
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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