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Record W4387313865 · doi:10.31080/asor.2023.06.0826

Muscle and Knee Osteoarthritis: “What’s New” in 2023

2023· article· en· W4387313865 on OpenAlex
Ray Marks

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueActa Scientific Orthopaedics · 2023
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsOsteoporosis CanadaResearch Canada
Fundersnot available
KeywordsOsteoarthritisPhysical medicine and rehabilitationMedicinePhysical therapyAlternative medicinePathology

Abstract

fetched live from OpenAlex

Osteoarthritis, the most common joint disease experienced by many older adults and one that is increasing as societies age remains largely incurable and highly disabling. As such, and in light of the failure of most palliative pharmacologic strategies to date to reverse or mitigate this painful condition, it appears all avenues of potential progress added to those already being explored may yet prove fruitful. Based on emerging and quite promising data outlining a possible link between aspects of osteoarthritis joint damage and muscle deficits, this mini-review elected to examine the most current data in regard to discern whether: 1) Muscle dysfunction continues to be an important potentially modifiable health determinant whose presence might influence the onset and progression of osteoarthritis through direct as well as indirect pathways, and 2) any evidence pointing to its possible detection, categorization, and remediation as being desirable in this regard if indicated. Based on the bulk of available data housed in PUBMED, GOOGLE SCHOLAR, Science Direct, and PubMed Central as of August 15, 2023, it is concluded that a causative, mediating or moderating role for muscle dysfunction in the realm of osteoarthritis cannot be ignored as per data related to its most common form, knee osteoarthritis. Future efforts to advance this line of inquiry that proceed from a multi component muscle specific and whole joint perspective of osteoarthritis disability may prove of immense personal and societal impact and benefit.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.647
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.259
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it