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Record W4387373285 · doi:10.5530/ijpcs.2023.12.3

Drug Review: Abrocitinib

2023· article· en· W4387373285 on OpenAlexaboutno aff
Juman Alsaab

Bibliographic record

VenueInternational Journal of Pharmacology and Clinical Sciences · 2023
Typearticle
Languageen
FieldMedicine
TopicCytokine Signaling Pathways and Interactions
Canadian institutionsnot available
Fundersnot available
KeywordsFormularyMedicineChristian ministryDrugDrug CompanyNew drug applicationFamily medicinePharmacologyPolitical scienceManagementLaw

Abstract

fetched live from OpenAlex

International Journal of Pharmacology and Clinical Sciences,2023,12,1,14-16.DOI:10.5530/ijpcs.2023.12.3Published:September 2023Type:Research ArticleAuthors:Juman Alsaab Author(s) affiliations:Juman Alsaab, Pharm D Ministry of Health, Riyadh, SAUDI ARABIA. Abstract:Registrations: Abrocitinib had been registered in the following countries United States of America (USA), United Kingdom (U.K.), Canada, and Saudi Arabia (SA). Trade name (USA.); CIBINQO® Registration number (S.A.); Not Available. Insurance Drug Formulary (S.A.); Not covered (28.1.2023). General Information: Registered Company: By Pfizer company. Regulatory Status: R.X. Mechanism of Action: It is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Indication Approved (Labeled) indication Atopic dermatitis (Moderate to Severe), Refractory to other systemic drug products, including biologics, or when the use of such therapies is inadvisable.[3] Read more.. View:PDF (264.11 KB) PDFClick here to download the PDF file. Images Drug Review: Cibinqo/abrocitinib

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.093
Threshold uncertainty score0.940

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.082
GPT teacher head0.513
Teacher spread0.431 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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