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Record W4387444791 · doi:10.33540/1982

We are all on the same team

2023· dissertation· en· W4387444791 on OpenAlexfundno aff
Annefleur Christel Langedijk

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsnot available
FundersMedical Research CouncilSanofi PasteurStanley Center for Psychiatric Research, Broad InstituteMinistry of Health of the Russian FederationTurun YliopistoJulius ClinicalSanofiUniversidade de Santiago de CompostelaKing's College LondonUniklinikum Giessen und MarburgSouth African Medical Research CouncilEuropean Federation of Pharmaceutical Industries and AssociationsInstituto de Salud Carlos IIINational Research FoundationMcMaster UniversityMcGill University Health CentreMcGill UniversityUniversità degli Studi di PadovaHarvard UniversitySeoul National UniversityEuropean CommissionBroad InstituteTurun Yliopistollinen KeskussairaalaAstraZeneca
KeywordsBusinessTransparency (behavior)ProcurementAccountabilityPrivate sectorPublic sectorPublic relationsMarketingPolitical scienceComputer securityComputer science

Abstract

fetched live from OpenAlex

The harmonious dance between academia and industry This is an exciting time for RSV research. With the recent approval of the first-ever RSV vaccines and monoclonal antibody (mAb) for all infants, we are on the cusp of major advances in the prevention of RSV disease. Of these RSV vaccines, many are a result of joint research between academia and industry. The rationale is that these PPPs overcome challenges in financing, implementation and delivery of infrastructure and public services, based on the assumption that the private sector brings additional finance and competence and that private companies are inherently more efficient than the public sector in delivering high-quality public services. While the concept of PPPs appears straightforward, the implementation may face multiple challenges. PPPs are complex as the value for money is often ethically questioned and the procurement processes can be lenghty because of legal and regulatory barriers. Lack of transparency and accountability may be the top barrier of PPPs, however, legal barriers including approval and permits and law and regulation changes may also slow down the process. With RSV prevention within reach and the potential risk of PPPs creating complex challenges, we have explored how PPPs co-create value in RSV research. Is industry-funded RSV research on balance beneficial? Clearly it is. Ultimately, the positives of PPPs in RSV research heavily outweigh the negatives. The question is not whether there may be conflicts of interest for – there are. Rather, the goal is to work around those and achieve a fair, transparent, unbiased, and scientifically valid result that benefits all. We cannot pretend that the public sector owns public health: promoting clarity and transparency in clinical research is an intrinsic public health good and a shared responsibility of both academia and industry. While pure academic research is an important adjuvant to industry-supported development, it cannot replace the focus or scope of industry funding. In the graceful choreography uniting academia and industry, the orchestrated symphony of PPPs unveils not just scientific advancements, but also weaves a melodic tapestry of collaborative determination that forges a future fortified against RSV.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.053
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.129
Threshold uncertainty score0.432

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0150.053
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.001
Science and technology studies0.0090.008
Scholarly communication0.0200.019
Open science0.0040.015
Research integrity0.0130.032
Insufficient payload (model declined to judge)0.1290.115

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.392
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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