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Record W4387480665 · doi:10.1515/chem-2023-0133

Prefatory<i>in silico</i>studies and<i>in vitro</i>insecticidal effect of<i>Nigella sativa</i>(L.) essential oil and its active compound (carvacrol) against the<i>Callosobruchus maculatus</i>adults (Fab), a major pest of chickpea

2023· article· en· W4387480665 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOpen Chemistry · 2023
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicInsect Pest Control Strategies
Canadian institutionsUniversité Laval
FundersKing Saud University
KeywordsCarvacrolCallosobruchus maculatusEssential oilNigella sativaCaryophylleneTraditional medicineToxicologyThymolChemistryBiologyHorticultureFood scienceMedicinePEST analysis

Abstract

fetched live from OpenAlex

Abstract To help discover a reasonable and eco-friendly insecticide, we undertook a study on the insecticidal potential of carvacrol and essential oils extracted by hydrodistillation using a Clevenger apparatus from the plant species Nigella sativa seeds essential oils of Nigella sativa (EONS) on Callosobruchus maculatus adults. Several tests including contact toxicity, repellent effect, topical contact test, and inhalation effect were conducted. Adults of C. maculatus have been exposed to the toxic effects of different concentrations of these essential oils as well as with carvacrol. The results obtained showed that both EONS and carvacrol exhibited a moderate repellent effect (class II) on C . maculatus adults. EONS showed the highest toxicity by inhalation test, with an LD 50 of 13.386 and an LD 95 of 33.186 μL/cm 2 , compared to carvacrol (LD 50 = 21.509 and LD 95 = 38.877 μL/cm 2 ). The EONS by contact test exhibited more toxic effects, with an LD 50 of 23.350 µL/100 g and an LD 95 of 45.315 µL/100 g, compared to carvacrol (LD 50 = 27.853 µL/100 g and LD 95 = 45.184 µL/100 g). For the topical contact test results, carvacrol was more toxic, with an LD 50 of 3.915 and an LD 95 of 7.696 µL/mL, compared to EONS (LD 50 = 14.509 and LD 95 = 25.516 µL/mL). The high toxicity of EONS can be explained by the presence of 25.8% of o -cymene, 8.53% of cyclofenchene, and 7.71% of beta-pinene, as well as 4.6% of carvacrol, in its chemical composition. Unmitigatedly, these data suggest that the essential oils of N. sativa may present a raw material for the development of new bio-insecticidal products against C. maculatus , one of the main pests of stored foodstuffs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.065
Threshold uncertainty score0.612

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.248
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it