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Record W4387730319 · doi:10.2337/cd23-0058

When Type 1 Diabetes Meets Dementia: Practical Strategies to Help Patients and Their Loved Ones

2023· article· en· W4387730319 on OpenAlexafffundabout
Ian Blumer, Medha Munshi, William H. Polonsky

Bibliographic record

VenueClinical Diabetes · 2023
Typearticle
Languageen
FieldMedicine
TopicDiabetes Management and Research
Canadian institutionsUniversity of Toronto
FundersBC Children's Hospital
KeywordsCitationIconLibrary scienceType 2 diabetesMedicineGerontologyDiabetes mellitusComputer science

Abstract

fetched live from OpenAlex

As the population ages, increasing numbers of people are affected by dementia.Individuals living with diabetes are at particular risk of cognitive decline as they age (1).This fact has been well documented with regard to people living with type 2 diabetes but has also been noted in those living with type 1 diabetes (2).Now, in the 21st century, as more people with type 1 diabetes are living longer (3), we should not be surprised when the need for addressing dementia and other late-age cognitive issues becomes more common in our clinical practices.Certain support strategies have been developed to assist individuals living with type 2 diabetes and dementia, and their caregivers, such as spouses or other loved ones.What has received far less attention, however, is the dilemma confronting individuals living with type 1 diabetes and dementia and, moreover, the sometimes dire challenges confronting their caregivers as they gamely, but often unsuccessfully, try to take on new roles in assisting with diabetes management (4,5). Meet Joanne**Joanne's story is a composite with some features changed to preserve patient confidentiality.Consider the case of Joanne, a 75-year-old woman with longstanding type 1 diabetes who was referred to one of us (I.R.B., or "Dr.B") for an initial consultation.After exchanging the usual introductory greetings and pleasantries, Dr. B asked Joanne how long she had had diabetes."Oh, a long time," she said as she smiled."Uhuh," he probed, "Like 10, 20, 30 years?" "Oh, at least," Joanne replied."Hmm," Dr. B thought.This was a surprisingly vague answer.Most people with type 1 diabetes recall with precision the details surrounding when they were diagnosed."And which insulin are you taking?" he asked."Lantus and Humalog," she quickly answered."Oh, okay, great.Thanks.And how much do you take?" "Ah, well," she hesitated, "it depends.I use a ratio.One unit for every 10 units.""One unit for every 10 units?" he thought."Well, maybe that was an innocent, misspoken comment.""So, how many units does that typically work out to for most of your meals?" he asked.Joanne shrugged, but did not respond."Like, on average," he continued, "would it be 2, 3 units?Or more like 20 or 30 units?" Joanne started to answer, then again fell silent."Joanne," Dr. B asked, "are you here with anybody today?" "Yes," she replied, "my husband, Frank, is here with me."She agreed to have her husband join them."Hi Frank," Dr. B said as Joanne's husband was ushered into the examining room."We were just discussing Joanne's diabetes.She said she's had it for a long time.""Oh yes," Frank replied, "even before we were married, and that was almost 50 years ago."Joanne indicated that it was okay to continue asking Frank questions."Frank," Dr. B said, "just to doublecheck a few things with you, can you confirm which types of insulin Joanne is taking?""I wouldn't know that," he quickly replied."Two types I think.""Oh, okay," Dr. B went on, "and how many units of them does she take?" "Oh, I wouldn't know that either," Frank said."Joanne looks after all of that.Always has." "Joanne," Dr. B said, as he again turned toward her, "how is your diabetes control?Do you know what your most recent A1C was?Or how often you're high or low?That sort of thing?" "Oh, I've got great control," Joanne quickly responded.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.027
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.153
Threshold uncertainty score0.512

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.027
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0050.002
Scholarly communication0.0080.010
Open science0.0020.010
Research integrity0.0070.009
Insufficient payload (model declined to judge)0.1530.081

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.087
GPT teacher head0.401
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes3
Has abstractyes

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