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HHT Virtual Imaging Case Conferences - A New Way Forward for Rare Disease Management

2023· article· en· W4387981716 on OpenAlexaffabout
Dilini Vethanayagam, Richard Owen, Hugo Bertozzi, Darshan Bakshi, Rohan Parab, Ani Mirakhur, Oliver Halliwell, Charlene D. Fell

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Rare Diseases
Canadian institutionsUniversity of CalgaryUniversity of Alberta
Fundersnot available
KeywordsMedicineOutreachMedical imagingLegislationTelehealthSession (web analytics)Medical educationHealth careMedical emergencyTelemedicineBusinessPolitical scienceRadiology

Abstract

fetched live from OpenAlex

Introduction: Interdisciplinary case conferences are known to improve patient care in multisystem diseases. Medical imaging in key affected organ systems is integral to effective HHT management. The health jurisdiction of Alberta, Canada has a province-wide mandate for medical imaging storage developed through federal and provincial grants, which has been a tremendous resource to develop case management discussions virtually. This connectivity of imaging provides opportunities to discuss cases from across many areas of the province. We aimed to develop a platform for HHT multi-disciplinary medical imaging case conferences across Alberta. Methods: Pilot work for HHT imaging case conferences was carried out in Edmonton (2003-2013). A structured approach to medical imaging case conferences was reviewed and optimized to ensure participation by rural areas, respecting appropriate data sharing, privacy legislation and patient consent. The province-wide interdisciplinary framework was deployed in 2014. Results: Province-wide HHT interdisciplinary imaging case conferences were initially deployed through AHS, and later via a secure on-line platform during the COVID pandemic. Team members include Respirologists, Interventional Radiologists, Neurologists, Geneticists, Hematologists, nurses, trainees and researchers with appropriate patient permission (4 sessions/yr, 2-3 cases/session). Conclusion: Deployment of province-wide HHT imaging case conferences allows participation by many clinicians, including those from rural areas of the province. Future directions include pursuing inter-provincial / territorial case conferences to facilitate broader outreach of diagnostic and therapeutic expertise in HHT medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.028
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.035
Threshold uncertainty score0.149

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0280.042
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0030.001
Science and technology studies0.0060.005
Scholarly communication0.0110.012
Open science0.0060.021
Research integrity0.0040.008
Insufficient payload (model declined to judge)0.0350.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.260
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

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