215 Compensatory Growth Following One or Two Weeks of Lysine Restriction at Weaning
Bibliographic record
Abstract
Abstract At weaning it is increasingly common to feed low crude protein (CP) and low standardized ileal digestible (SID) lysine (LYS) diets for improved health outcomes. This nutrient restriction often leads to decreased growth. Compensatory growth in this discussion is a period of enhanced growth that occurs after a period of nutrient restriction. This experiment was conducted to determine if compensatory growth occurs after one or two-weeks restriction of SID LYS at weaning. For the experiment, pigs (n = 252; ~23.5 days of age, 7.24 ± 1.02 kg BW, 8 reps/treatmentt, 5 or 6 pigs/pen) were randomly allotted to one of six treatments in a randomized complete block design with a 2 x 3 factorial arrangement of treatments. Treatment main effects were SID LYS/CP (0.07 or 0.065) or duration of SID LYS restriction (1.2% SID LYS for 0, 1, or 2 weeks). When not restricted, pigs were fed a diet with 1.5% SID LYS. After the first 14 days, all pigs consumed a common diet for 24 days with 1.35% SID LYS. Body weight, feed disappearance, visual fecal scores, and visual piglet scores were measured. Visual fecal scores (1 = normal to 4 = watery) and visual pig appearance scores (1 = pale and hairy to 4 = normal color and well-rounded muscle) were assessed on ordered likert scales to determine the probabilities of observing a more normal stool quality and a worse visual appearance, respectively. Performance data were analyzed as a general linear model. Stool quality and visual appearance were analyzed as a generalized linear mixed model. Pairwise comparisons with Tukey adjustment were used for treatment LSmean separation. No effect of SID LYS/CP or interaction of SID LYS/CP and SID LYS program was detected. Results for the main effect of SID LYS program is presented in Table 1. Restricting SID LYS for the first week resulted in decreased ADG and gain:feed (P < 0.05; Table 1). This same effect was observed in week 2. However, those pigs that moved from 1.2% SID LYS in week 1 to 1.5% SID LYS in week 2 had the similar ADG and gain:feed during week 2 as the pigs that consumed 1.5% SID LYS for both weeks. Pigs that had two weeks of SID LYS restriction had lower body weight at d 38 (P< 0.05), whereas pigs with one week of SID LYS restriction had similar body weight at d 38 to unrestricted LYS fed pigs. In addition to performance, unrestricted LYS decreased stool quality (P<0.05) but improved the visual appearance of pigs (P < 0.10) at d 14 and d 38. In conclusion, pigs can have compensatory growth when SID LYS is restricted from 1.5% to 1.2% for one week, but not two weeks.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".