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Record W4388336370 · doi:10.1016/j.ajt.2023.10.031

The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts

2023· article· en· W4388336370 on OpenAlexaffabout
Candice Roufosse, Maarten Naesens, Mark Haas, Carmen Lefaucheur, Roslyn B. Mannon, Marjan Afrouzian, Nada Alachkar, Olivier Aubert, Serena M. Bagnasco, Ibrahim Batal, Christopher Bellamy, Verena Broecker, Klemens Budde, Marian C. Clahsen‐van Groningen, Shana M. Coley, Lynn D. Cornell, Darshana M. Dadhania, Anthony J. Demetris, Gunilla Einecke, Alton B. Farris, Agnes B. Fogo, John J. Friedewald, Ian W. Gibson, Catherine Horsfield, Edmund Huang, S. Ali Husain, Annette M. Jackson, Jesper Kers, Željko Kikić, Amanda Klein, Nicolas Kozakowski, Helen Liapis, Massimo Mangiola, Robert A. Montgomery, Brian Nankinvell, Desley Neil, Peter Nickerson, Marion Rabant, Parmjeet Randhawa, Leonardo V. Riella, Ivy A. Rosales, Virginie Royal, Ruth Sapir‐Pichhadze, Pinaki Sarder, Minnie Sarwal, Carrie A. Schinstock, Mark D. Stegall, Kim Solez, Jeroen van der Laak, Chris Wiebe, Robert B. Colvin, Alexandre Loupy, Michael Mengel

Bibliographic record

VenueAmerican Journal of Transplantation · 2023
Typearticle
Languageen
FieldMedicine
TopicRenal Transplantation Outcomes and Treatments
Canadian institutionsMcGill UniversityUniversity of AlbertaUniversité de MontréalHôpital Maisonneuve-RosemontUniversity of Manitoba
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesCareDxCSL Behring
KeywordsMedicineUrology

Abstract

fetched live from OpenAlex

The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada, from September 19 to 23, 2022, as a joint meeting with the Canadian Society of Transplantation. In addition to a key focus on the impact of microvascular inflammation and biopsy-based transcript analysis on the Banff Classification, further sessions were devoted to other aspects of kidney transplant pathology, in particular T cell-mediated rejection, activity and chronicity indices, digital pathology, xenotransplantation, clinical trials, and surrogate endpoints. Although the output of these sessions has not led to any changes in the classification, the key role of Banff Working Groups in phrasing unanswered questions, and coordinating and disseminating results of investigations addressing these unanswered questions was emphasized. This paper summarizes the key Banff Meeting 2022 sessions not covered in the Banff Kidney Meeting 2022 Report paper and also provides an update on other Banff Working Group activities relevant to kidney allografts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.241
metaresearch head score (Gemma)0.258
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.759
Threshold uncertainty score0.936

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2410.258
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0100.007
Science and technology studies0.0050.003
Scholarly communication0.0130.007
Open science0.0070.012
Research integrity0.0040.009
Insufficient payload (model declined to judge)0.0180.015

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.323
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations49
Published2023
Admission routes2
Has abstractyes

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Same venueAmerican Journal of TransplantationSame topicRenal Transplantation Outcomes and TreatmentsFrench-language works237,207