Comparison of Intra-articular Steroid and Platelet-Rich Plasma Injections in Patients With Knee Osteoarthritis
Bibliographic record
Abstract
INTRODUCTION: This study aimed to compare the effects of intra-articular steroid (IAS) and platelet-rich plasma (PRP) injections on femoral cartilage thickness and quality of life in patients with knee osteoarthritis (OA). METHODS: This research was designed as a retrospective study with propensity score matching and included 80 treatment-naive patients with knee OA. All patients' demographic characteristics and Visual Analog Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Short Form-36 (SF-36) scores before treatment, one month after treatment, and six months after treatment were recorded. Femoral cartilage thickness measurements were taken with ultrasonography. To determine the efficiency of IAS and PRP injections, data was collected before treatment, one month after treatment, and six months after treatment and then compared. RESULTS: All VAS values and WOMAC scores were significantly better one month and six months after treatment in both the IAS group and PRP group. However, IAS treatment was associated with significantly lower VAS scores during the night and during movement one month after treatment (p=0.044 and p=0.042). VAS at rest and the WOMAC scores one month after treatment were similar (p=0.435 and p=0.616). All VAS scores (night, rest, and movement) and WOMAC scores were comparable between groups six months after treatment (p=0.569, p=0.504, p=0.584, and p=0.441). There were no significant differences in femoral thickness at the eight measurement points between the groups at the follow-ups. CONCLUSION: Our findings have shown that IAS and PRP injection treatments have a significantly positive effect on the pain and quality of life of patients with knee OA, although this positive effect for pain was significantly better for IAS at night and during movement at the one-month follow-up. Additionally, IAS and PRP injections had positive and comparable healing impacts on femoral cartilage thickness.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".