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Record W4388452102 · doi:10.25071/2817-5344/56

Public Sector Contribution to Vaccine Research and Development

2023· article· en· W4388452102 on OpenAlexaff
E. Cary Brown

Bibliographic record

VenueCanadian Journal for the Academic Mind · 2023
Typearticle
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsMcMaster University
Fundersnot available
KeywordsPrivate sectorGovernment (linguistics)BusinessPublic sectorInvestment (military)ProcurementIntellectual propertyGovernment procurementIncentivePublic policyPublic economicsEconomic growthEconomicsPolitical scienceMarket economyMarketingPoliticsEconomy

Abstract

fetched live from OpenAlex

This paper explores the public sector’s often undersold role in vaccine research and development (R&D). Further, it examines the recent shift in vaccine innovation policy caused by the urgency of the COVID-19 pandemic. Due to factors such as lack of repetitive dosage, high levels of at-risk investment, and long, large clinical trials, it is difficult to incentivize the private sector to invest in vaccine R&D. To counter these difficulties, vaccine innovation policy focuses on both push and pull incentives to ensure vaccine R&D is proceeding. Government institutions make large at-risk investments to offset the risk for private sector investment into vaccine R&D. Additionally, the government creates innovation policies that make intellectual property rights (IPR) more favourable for those who invest in vaccine R&D. With the removal of IPR for COVID-19 vaccines, the public sector became more instrumental in incentivizing private sector investment, using techniques such as mass ex-ante government vaccine procurement agreements, public-private partnerships, and increased government investments. With more significant government investments in downstream development and manufacturing activities, there is concern that the basic scientific research required for advances in vaccine technology will diminish. With the COVID-19 pandemic still unfolding, it is difficult to determine whether vaccine innovation policy will remain as it is now. However, even if vaccine innovation policy shifts post-pandemic, the public sector must continue to play an important role in vaccine R&D.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.229
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0030.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.241
GPT teacher head0.403
Teacher spread0.162 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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