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Record W4388751367 · doi:10.1016/j.bpsc.2023.10.012

Cognition and Educational Achievement in the Toronto Adolescent and Youth Cohort Study: Rationale, Methods, and Early Data

2023· article· en· W4388751367 on OpenAlexafffundabout
Lena C. Quilty, Wanda Tempelaar, Brendan F. Andrade, Sean A. Kidd, Yona Lunsky, Sheng Chen, Wei Wang, Jimmy K Y Wong, Chloé Lau, Andrew B Sedrak, Rachel Kelly, Melanie Jani, Stephanie H. Ameis, Kristin Cleverley, Benjamin I. Goldstein, Daniel Felsky, Erin W. Dickie, George Foussias, Nicole Kozloff, Yuliya S. Nikolova, Alexia Polillo, Andreea O. Diaconescu, Anne L. Wheeler, Darren Courtney, Lisa D. Hawke, Martin Rotenberg, Aristotle N. Voineskos

Bibliographic record

VenueBiological Psychiatry Cognitive Neuroscience and Neuroimaging · 2023
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsMental Health Research CanadaWestern UniversityCentre for Addiction and Mental Health
FundersDepartment of Psychiatry, Faculty of Medicine, University of British ColumbiaCanadian Institutes of Health ResearchNational Institute of Mental HealthSocial Sciences and Humanities Research Council of CanadaMargaret and Wallace McCain Centre for Child, Youth and Family Mental HealthDepartment of Psychiatry, University of TorontoCundill Centre for Child and Youth DepressionMitacsUniversity of TorontoCanarieOntario Brain InstituteArcus FoundationFondation Brain CanadaRainwater Charitable FoundationOntario HIV Treatment NetworkAzrieli FoundationNatural Sciences and Engineering Research Council of CanadaMinistère de la Défense NationaleCentre for Addiction and Mental Health FoundationGovernment of OntarioPeter Gilgan FoundationMental Health Research CanadaJ.W. McConnell Family FoundationKrembil FoundationCanada Foundation for InnovationRoyal Bank of CanadaCentre for Addiction and Mental HealthWellcome TrustOntario Research FoundationNovartis FoundationHospital for Sick ChildrenHeart and Stroke Foundation of CanadaNational Institutes of HealthRobert Wood Johnson Foundation
KeywordsCognitionPsychologyCohortPopulationWechsler Adult Intelligence ScaleCognitive testClinical psychologyDevelopmental psychologyMedicinePsychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Both cognition and educational achievement in youths are linked to psychosis risk. One major aim of the Toronto Adolescent and Youth (TAY) Cohort Study is to characterize how cognitive and educational achievement trajectories inform the course of psychosis spectrum symptoms (PSSs), functioning, and suicidality. Here, we describe the protocol for the cognitive and educational data and early baseline data. METHODS: The cognitive assessment design is consistent with youth population cohort studies, including the NIH Toolbox, Rey Auditory Verbal Learning Test, Wechsler Matrix Reasoning Task, and Little Man Task. Participants complete an educational achievement questionnaire, and report cards are requested. Completion rates, descriptive data, and differences across PSS status are reported for the first participants (N = 417) ages 11 to 24 years, who were recruited between May 4, 2021, and February 2, 2023. RESULTS: Nearly 84% of the sample completed cognitive testing, and 88.2% completed the educational questionnaire, whereas report cards were collected for only 40.3%. Modifications to workflows were implemented to improve data collection. Participants who met criteria for PSSs demonstrated lower performance than those who did not on numerous key cognitive indices (p < .05) and also had more academic/educational problems. CONCLUSIONS: Following youths longitudinally enabled trajectory mapping and prediction based on cognitive and educational performance in relation to PSSs in treatment-seeking youths. Youths with PSSs had lower cognitive performance and worse educational outcomes than youths without PSSs. Results show the feasibility of collecting data on cognitive and educational outcomes in a cohort of youths seeking treatment related to mental illness and substance use.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.407
Threshold uncertainty score0.810

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0140.016
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0030.006
Science and technology studies0.0040.002
Scholarly communication0.0020.001
Open science0.0030.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.156
GPT teacher head0.425
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2023
Admission routes3
Has abstractyes

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