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Record W4388760922 · doi:10.1021/acs.organomet.3c00362

Mechanism of Perfluoro-Nickelacyclopentane Formation from Tetrafluoroethylene: Effects of Ancillary Ligand Bite Angle

2023· article· en· W4388760922 on OpenAlexafffund
Luana L. T. N. Porto, Behnaz Ghaffari, Jeffrey S. Ovens, Russell P. Hughes, R. Tom Baker

Bibliographic record

VenueOrganometallics · 2023
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicFluorine in Organic Chemistry
Canadian institutionsUniversity of Ottawa
FundersArkemaNatural Sciences and Engineering Research Council of CanadaMitacs
KeywordsBite angleChemistryMetallacycleDenticityLigand (biochemistry)Trigonal bipyramidal molecular geometryTransition stateChelationStereochemistryPhosphineCrystallographyPhotochemistryCatalysisCrystal structureOrganic chemistryX-ray crystallography

Abstract

fetched live from OpenAlex

Metallacyclopentanes are important reaction intermediates for catalytic processes, such as selective ethylene oligomerization and diene cyclooligomerization. Reactions of fluoroalkenes with low-valent first row transition metal complexes tend to form stable fluorometallacyclopentane products. DFT studies conducted herein indicate that conversion of three-coordinate Ni(η 2 -C 2 F 4 )L 2 complexes (L 2 = 2 monodentate or one bidentate chelate) to perfluorometallacycle products Ni[κ 2 -(CF 2 ) 4 -]L 2 occurs preferentially via a four-coordinate intermediate Ni(η 2 -C 2 F 4 ) 2 L 2; an alternative three-coordinate pathway via Ni(η 2 -C 2 F 4 ) 2 L occurs only when L is extremely bulky. The transition structure for cyclization requires a dramatic increase in the L–Ni–L angle, which is perpendicular to the C–C bond-forming plane and initially affords a kinetic metallacycle intermediate resembling a trigonal bipyramidal geometry with one equatorial vacant site. The donor solvent, or intramolecular O-donor association with this intermediate, provides a low-energy pathway to the formation of the more stable square-planar metallacycle product. For bidentate chelate ligands, differential bite angles affect both coordination of a second C 2 F 4 ligand and the cyclization step. For small-bite-angle chelates, the cyclization transition state energies are higher relative to monodentate analogues. An experimental investigation of wide bite-angle bis(phosphine) ligands such as DPEphos and Bisbi showed the formation of additional nickelacyclopentane products with the coordination of a single P center to each Ni [DPEphos = bis(2-diphenylphosphino-phenyl) ether; Bisbi = 2,2′-bis(diphenylphosphino-methyl)-1,1′-biphenyl].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.343
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2023
Admission routes2
Has abstractyes

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