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Record W4388931413 · doi:10.31222/osf.io/5sehd

Research Ethics Committees as an intervention point to promote a priori sample size calculations

2023· preprint· en· W4388931413 on OpenAlexfundno aff
Sofia Papalouka, Márton Kovács, Marcus R. Munafò, Robert T. Thibault

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsnot available
FundersMedical Research CouncilCanadian Institutes of Health ResearchArnold Ventures
KeywordsSample size determinationSample (material)Research ethicsResearch designPsychologyMedical educationSociologyMedicineStatisticsSocial scienceMathematics

Abstract

fetched live from OpenAlex

Studies in the health and life sciences often use sample sizes too small to robustly answer the research questions at hand. By performing a formal sample size calculation before beginning a study, researchers can overcome this issue. One potential avenue to promote the uptake of sample size calculation is through Research Ethics Committees (RECs). We assessed template ethics submission forms from 10 RECs from research-intensive universities in each of the United States and the United Kingdom (for 20 forms in total). We found that 19 of them requested that researchers provide the planned sample size, 12 requested a justification of the sample size, and 6 requested a sample size calculation. Future research could investigate the effectiveness of sample size requests from RECs and compare this approach to intervening through other mechanisms, such as Scientific Review Committees or funding agencies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.658
metaresearch head score (Gemma)0.778
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: Methods
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.342
Threshold uncertainty score0.422

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.6580.778
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0090.007
Science and technology studies0.0060.007
Scholarly communication0.0080.009
Open science0.0050.008
Research integrity0.0070.012
Insufficient payload (model declined to judge)0.0200.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.807
GPT teacher head0.705
Teacher spread0.102 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2023
Admission routes1
Has abstractyes

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