Acute intermittent hypoxia in people living with chronic stroke – a preliminary study to examine safety and efficacy as a neurorehabilitation intervention
Bibliographic record
Abstract
ABSTRACT Background and Purpose Acute intermittent hypoxia (AIH) is a novel therapeutic intervention that has the potential to facilitate recovery of function, but its safety and efficacy have not been tested in people with stroke. The purpose here was to examine whether AIH is safe and effective in people with stroke. Methods Participants (n=10) with a unilateral, ischemic, hemispheric stroke were assessed before and following 4 sessions of AIH. Clinical tests and upper limb strength were assessed before, ∼15-30 minutes, and ∼60 minutes after the intervention. Results AIH was well-tolerated and there were no adverse events observed. Although no changes in strength were detected for the less-affected limb, grip strength and elbow flexion force of the more-affected limb was increased after AIH. Conclusions AIH appears to be potentially safe and effective for improving strength in the more-affected limb in people with stroke. Future work should explore the use of AIH to enhance task-specific training-induced plasticity.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".