MétaCan
Menu
Back to cohort
Record W4389787895 · doi:10.1161/strokeaha.123.043033

Code ICH: A Call to Action

2023· article· en· W4389787895 on OpenAlexaff
Qi Li, Aleksandra Yakhkind, Anne W. Alexandrov, Andrei V. Alexandrov, Craig S. Anderson, Dar Dowlatshahi, Jennifer Frontera, J. Claude Hemphill, Latha Ganti, Chris Kellner, Casey C. May, Andrea Morotti, Adrian Parry‐Jones, Kevin N. Sheth, Thorsten Steiner, Wendy Ziai, Joshua N. Goldstein, Stephan A. Mayer

Bibliographic record

VenueStroke · 2023
Typearticle
Languageen
FieldMedicine
TopicIntracerebral and Subarachnoid Hemorrhage Research
Canadian institutionsOttawa Hospital
Fundersnot available
KeywordsMedicineIntracerebral hemorrhagePsychological interventionIntensive care medicineHematomaRandomized controlled trialStroke (engine)Intervention (counseling)Best practiceStandard of careSurgerySubarachnoid hemorrhageNursing

Abstract

fetched live from OpenAlex

Intracerebral hemorrhage is the most serious type of stroke, leading to high rates of severe disability and mortality. Hematoma expansion is an independent predictor of poor functional outcome and is a compelling target for intervention. For decades, randomized trials aimed at decreasing hematoma expansion through single interventions have failed to meet their primary outcomes of statistically significant improvement in neurological outcomes. A wide range of evidence suggests that ultra-early bundled care, with multiple simultaneous interventions in the acute phase, offers the best hope of limiting hematoma expansion and improving functional recovery. Patients with intracerebral hemorrhage who fail to receive early aggressive care have worse outcomes, suggesting that an important treatment opportunity exists. This consensus statement puts forth a call to action to establish a protocol for Code ICH, similar to current strategies used for the management of acute ischemic stroke, through which early intervention, bundled care, and time-based metrics have substantially improved neurological outcomes. Based on current evidence, we advocate for the widespread adoption of an early bundle of care for patients with intracerebral hemorrhage focused on time-based metrics for blood pressure control and emergency reversal of anticoagulation, with the goal of optimizing the benefit of these already widely used interventions. We hope Code ICH will endure as a structural platform for continued innovation, standardization of best practices, and ongoing quality improvement for years to come.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.107
metaresearch head score (Gemma)0.169
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.107
Threshold uncertainty score0.567

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1070.169
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0070.008
Bibliometrics0.0040.003
Science and technology studies0.0080.019
Scholarly communication0.0160.033
Open science0.0110.016
Research integrity0.0990.101
Insufficient payload (model declined to judge)0.0320.018

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.373
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations148
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueStrokeSame topicIntracerebral and Subarachnoid Hemorrhage ResearchFrench-language works237,207