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Cancer Related Cognitive Impairment in Breast Cancer Survivors: A Case - Control Study of Karnataka, India

2023· article· en· W4389951761 on OpenAlexaboutno aff
Vaishali C. Venugopal, K. Latha, M Kishor, Mohan Arunkumar, Vinitha Venugopal, Sowmya Balasubramanian

Bibliographic record

VenueMedical Journal of Dr D Y Patil Vidyapeeth · 2023
Typearticle
Languageen
FieldMedicine
TopicCancer-related cognitive impairment studies
Canadian institutionsnot available
Fundersnot available
KeywordsBreast cancerMedicineAnxietyMontreal Cognitive AssessmentHamilton Anxiety Rating ScaleDepression (economics)CognitionOutpatient clinicRating scaleCancerQuality of life (healthcare)Hamilton Rating Scale for DepressionHospital Anxiety and Depression ScalePopulationInternal medicinePhysical therapyClinical psychologyPsychiatryCognitive impairmentPsychologyMajor depressive disorder

Abstract

fetched live from OpenAlex

A BSTRACT Background: Breast cancer patients report difficulties with concentration, multi-tasking, and memory. Cognitive dysfunction can impact the quality of life by affecting activities of daily living, treatment compliance, interpersonal relationships, and profession. Aims: The objective of this study was to evaluate and compare the cognitive functions and psychological complications in breast cancer patients with a control population. Settings and Design: This study was conducted in the outpatient department of Bharath Hospital and Institute of Oncology, Mysore, where the cases were recruited. The study participants were 110 female breast cancer patients and 100 noncancer healthy females as controls. Materials and Methods: Demographic details of the participants were collected through a questionnaire. Clinical data were obtained from clinical records. Tools used were Montreal Cognitive Assessment (MoCA), Hamilton Depression Rating Scale (HAM-D), and Hamilton Anxiety Rating Scale (HAM-A) to evaluate cognitive functions, depression, and anxiety, respectively. Statistical Analysis: The various findings were analyzed using mean, frequency, Pearson’s correlation, and two-sample t -test. Results: Mild cognitive impairment was observed in 88% of the cancer patients, and more than 95% were under severe anxiety and depression. There is a highly significant difference in all three tests (MoCA Test, HAM-D test, HAM-A test) with a P < 0.001. Conclusion: Breast cancer patients show statistically significant cognitive deficits as compared to noncancer individuals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.332
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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