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Record W4390545294 · doi:10.1128/jvi.01791-23

Virology—the path forward

2024· article· en· W4390545294 on OpenAlexaff
Angela L. Rasmussen, Gigi Kwik Grönvall, Anice C. Lowen, Felicia Goodrum, James C. Alwine, Kristian G. Andersen, Simon J. Anthony, Joel D. Baines, Arinjay Banerjee, Andrew J. Broadbent, Christopher B. Brooke, Samuel K. Campos, Patrizia Caposio, Arturo Casadevall, Gary C. Chan, Anna R. Cliffe, Donna Collins-McMillen, Nancy Connell, Blossom Damania, Matthew D. Daugherty, Kari Debbink, Terence S. Dermody, Daniel DiMaio, W. Paul Duprex, Michael Emerman, Denise A. Galloway, Robert F. Garry, Stephen A. Goldstein, Alexander L. Greninger, Amy L. Hartman, Brenda G. Hogue, Stacy M. Horner, Peter J. Hotez, Jae U. Jung, Jeremy P. Kamil, Stephanie M. Karst, Lou Laimins, Seema S. Lakdawala, Igor Landais, Michael Letko, Brett D. Lindenbach, Shan‐Lu Liu, Micah A. Luftig, Grant McFadden, Andrew Mehle, Juliet Morrison, Anne Moscona, Elke Mühlberger, Joshua Munger, Karl Münger, Eain A. Murphy, Christopher J. Neufeldt, Janko Nikolich‐Žugich, Christine M. O’Connor, Andrew Pekosz, Sallie R. Permar, Julie K. Pfeiffer, Saskia Popescu, John G. Purdy, Vincent R. Racaniello, Charles M. Rice, Jonathan A. Runstadler, Martin Sapp, Rona S. Scott, Gregory A. Smith, Erin M. Sorrell, Emily Speranza, Daniel N. Streblow, Scott A. Tibbetts, Zsolt Tóth, Koenraad Van Doorslaer, Susan R. Weiss, Elizabeth White, Timothy M. White, Christiane E. Wobus, Michael Worobey, Satoko Yamaoka, Andrew D. Yurochko

Bibliographic record

VenueJournal of Virology · 2024
Typearticle
Languageen
FieldMedicine
TopicViral gastroenteritis research and epidemiology
Canadian institutionsUniversity of Saskatchewan
FundersNational Institute of Allergy and Infectious DiseasesNational Institute of General Medical Sciences
KeywordsBiologyVirologyPath (computing)Computational biologyComputer science

Abstract

fetched live from OpenAlex

In the United States (US), biosafety and biosecurity oversight of research on viruses is being reappraised. Safety in virology research is paramount and oversight frameworks should be reviewed periodically. Changes should be made with care, however, to avoid impeding science that is essential for rapidly reducing and responding to pandemic threats as well as addressing more common challenges caused by infectious diseases. Decades of research uniquely positioned the US to be able to respond to the COVID-19 crisis with astounding speed, delivering life-saving vaccines within a year of identifying the virus. We should embolden and empower this strength, which is a vital part of protecting the health, economy, and security of US citizens. Herein, we offer our perspectives on priorities for revised rules governing virology research in the US.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.066
metaresearch head score (Gemma)0.055
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.066
Threshold uncertainty score0.347

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0660.055
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.002
Science and technology studies0.0060.037
Scholarly communication0.0210.032
Open science0.0030.010
Research integrity0.0220.035
Insufficient payload (model declined to judge)0.0130.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.345
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2024
Admission routes1
Has abstractyes

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