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Record W4390547643 · doi:10.1093/bjsopen/zrad107

Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort

2024· article· en· W4390547643 on OpenAlexaff
Stefano Guadagni, Marco Catarci, Francesco Masedu, Mohammad Ehsanul Karim, Marco Clementi, Giacomo Ruffo, Massimo Viola, Felice Borghi, Giànandrea Baldazzi, Marco Scatizzi, Felice Pirozzi, Paolo Delrio, Gianluca Garulli, Pierluigi Marini, Roberto Campagnacci, Raffaele De Luca, Ferdinando Ficari, Giuseppe Sica, Stefano Scabini, Andrea Liverani, Marco Caricato, Alberto Patriti, Stefano Mancini, Gian Luca Baiocchi, Roberto Santoro, Walter Siquini, Gianluca Guercioni, Massimo Basti, Corrado Pedrazzani, Mauro Totis, A. Carrara, Andrea Lucchi, Maurizio Pavanello, Andrea Muratore, Stefano D’Ugo, Alberto Di Leo, Giusto Pignata, Ugo Elmore, Gabriele Anania, Massimo Carlini, Francesco Corcione, Nereo Vettoretto, Graziano Longo, Mario Sorrentino, Antonio Giuliani, Giovanni Ferrari, Lucio Taglietti, Augusto Verzelli, Mariantonietta Di Cosmo, Davide Cavaliere, Marco Milone, Stefano Rausei, Giovanni Ciaccio, Giovanni Domenico Tebala, Giuseppe Brisinda, Stefano Berti, Paolo Millo, Luigi Boni, Mario Guerrieri, Roberto Persiani, Dario Parini, Antonino Spinelli, Michele Genna, Vincenzo Bottino, Andrea Coratti, Dario Scala, Umberto Rivolta, Micaela Piccoli, Carlo Talarico, Franco Roviello, Alessandro Anastasi, Giuseppe Maria Ettorre, Mauro Montuori, Pierpaolo Mariani, Nicolò de Manzini, Annibale Donini, Mariano Fortunato Armellino, Carlo V. Feo, Silvio Guerriero, Andrea Costanzi, Federico Marchesi, Moreno Cicetti, Paolo Ciano, Michele Benedetti, L Montemurro, Maria Sole Mattei, Elena Belloni, Daniela Apa, Matteo Di Carlo, Elisa Bertocchi, Gaia Masini, Amedeo Altamura, Francesco Rubichi, D Cianflocca, Diletta Cassini, Lorenzo Pandolfini, Alessandro Falsetto, Antonio Sciuto, Ugo Pace, Andrea Fares Bucci, Francesco Monari, Grazia Maria Attinà, Angela Maurizi, Michele De Simone, Francesco Giudici, Fabio Cianchi, Bruno Sensi, Alessandra Aprile, Domenico Soriero, Andrea Scarinci, Gabriella Teresa Capolupo, Valerio Sisti, Marcella Lodovica Ricci, Andrea Sagnotta, Sarah Molfino, Pietro Maria Amodio, Alessandro Cardinali, Simone Cicconi, Irene Marziali, Diletta Frazzini, Cristian Conti, Nicolò Tamini, Marco Braga, Michele Motter, Giuseppe Tirone, Giacomo Martorelli, Alban Cacurri, Carlo Di Marco, Patrizia Marsanic, Nicoletta Sveva Pipitone Federico, Marcello Spampinato, Lorenzo Crepaz, Jacopo Andreuccetti, Ilaria Canfora, Giulia Maggi, Matteo Chiozza, Domenico Spoletini, Rosa Marcellinaro, Umberto Bracale, Roberto Peltrini, Maria Michela Di Nuzzo, Emanuele Botteri, Simone Santoni, Massimo Stefanoni, Giovanni Del Vecchio, Carmelo Magistro, S. Ruggiero, Arianna Birindelli, Andrea Budassi, Daniele Zigiotto, Leonardo Solaini, Giorgio Ercolani, Giovanni Domenico De Palma, Silvia Tenconi, Paolo Locurto, Antonio Di Cintio, Maria Michela Chiarello, Maria Cariati, Andrea Gennai, Manuela Grivon, Elisa Cassinotti, Monica Ortenzi, Alberto Biondi, Maurizio De Luca, Francesco Maria Carrano, Francesca Fior, Antonio Ferronetti, Giuseppe Giuliani, Graziella Marino, Camillo Leonardo Bertoglio, Francesca Pecchini, Vincenzo Greco, Roberto Piagnerelli, Giuseppe Canonico, Marco Colasanti, Enrico Pinotti, Roberta Carminati, Edoardo Osenda, Luigina Graziosi, Ciro De Martino, Giovanna Ioia, Fioralba Pindozzi, Lorenzo Organetti, Michela Monteleone, Giorgio Dalmonte, Gabriele La Gioia

Bibliographic record

VenueBJS Open · 2024
Typearticle
Languageen
FieldMedicine
TopicColorectal Cancer Surgical Treatments
Canadian institutionsCentre for Advancing Health OutcomesSt. Paul's HospitalUniversity of British Columbia
Fundersnot available
KeywordsMedicinePropensity score matchingColorectal surgerySurgeryAbdominal surgeryOdds ratioRetrospective cohort studyClinical endpointLogistic regressionMortality rateInternal medicineRandomized controlled trial

Abstract

fetched live from OpenAlex

BACKGROUND: In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim of this study was to evaluate the impact of abdominal drain placement on early adverse events in patients undergoing elective colorectal surgery. METHODS: A database was retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. The primary endpoint was the postoperative duration of stay, and the secondary endpoints were surgical site infections, infectious morbidity rate defined as surgical site infections plus pulmonary infections plus urinary infections, anastomotic leakage, overall morbidity rate, major morbidity rate, reoperation and mortality rates. The results of multiple logistic regression analyses were presented as odds ratios (OR) and 95 per cent c.i. RESULTS: A total of 6157 patients were analysed to produce two well-balanced groups of 1802 patients: group (A), no abdominal drain(s) and group (B), abdominal drain(s). Group A versus group B showed a significantly lower risk of postoperative duration of stay >6 days (OR 0.60; 95 per cent c.i. 0.51-0.70; P < 0.001). A mean postoperative duration of stay difference of 0.86 days was detected between groups. No difference was recorded between the two groups for all the other endpoints. CONCLUSION: This study confirms that placement of abdominal drain(s) after elective colorectal surgery is associated with a non-clinically significant longer (0.86 days) postoperative duration of stay but has no impact on any other secondary outcomes, confirming that abdominal drains should not be used routinely in colorectal surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.320
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2024
Admission routes1
Has abstractyes

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