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Fine needle aspiration cytology (FNAC) Vis-a-Vis histopathology for the diagnosis of canine hepatoid gland carcinoma - A case study

2023· article· en· W4390622893 on OpenAlexaboutno aff
Monika Thakur, Kuldip Gupta, Ramandeep, Neha Chauhan, Arvind Sharma

Bibliographic record

VenueIndian Journal of Veterinary Pathology · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHedgehog Signaling Pathway Studies
Canadian institutionsnot available
Fundersnot available
KeywordsHistopathologyFine needle aspiration cytologyCytologyMedicinePathologyFine-needle aspirationHistopathological examinationCarcinomaRadiologyBiopsy

Abstract

fetched live from OpenAlex

Hepatoid gland carcinomas (HGC) are relatively uncommon and accounts for 3-7% of all perianal neoplasms in canines. The present communication reports cytological, histopathological and radiographic findings in a rare case of hepatoid gland carcinoma involving tail region in eleven year old uncastrated male Labrador dog. On clinical examination, a solitary, raised, pea sized nodular mass was found over the proximal one third of the base of the tail. A routine complete blood count analysis was performed which showed borderline neutrophilic leucocytosis. Cytologic specimens prepared by Fine Needle Aspiration (FNA) revealed large hepatoid cells in sheets/clusters with vesicular nucleus and hyperchromatic nucleolus. Histopathological examination of excised mass revealed well-differentiated hepatoid cell population characterized by ample cytoplasm, eosinophilic granules and round nuclei with coarse chromatin. Thoracic radiographs revealed evidence of metastases in the lungs. Based on cytological and histopathological findings the mass was diagnosed as hepatoid gland carcinoma. The findings suggest that the FNAC technique could be of great use in the early presumptive diagnosis of canine hepatoid gland tumors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.389
Threshold uncertainty score0.771

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.317
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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