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Record W4390656896 · doi:10.1101/2024.01.03.573822

A Neural Network for High-Precise and Well-Interpretable Electrocardiogram Classification

2024· preprint· en· W4390656896 on OpenAlexaff
Xiaoqiang Liu, Liang He, Jiadong Yan, Yisen Huang, Yubin Wang, Chanchan Lin, Yingxuan Huang, Xiaobo Liu

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldMedicine
TopicECG Monitoring and Analysis
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersFujian Medical University
KeywordsInterpretabilityComputer scienceArtificial intelligenceClassifier (UML)Machine learningArtificial neural networkPattern recognition (psychology)EncoderTransformerEngineering

Abstract

fetched live from OpenAlex

Abstract Manual heart disease diagnosis with the electrocardiogram (ECG) is intractable due to the intertwined signal features and lengthy diagnosis procedure, especially for the 24-hour dynamic ECG signals. Consequently, even experienced cardiologists may face difficulty in producing all accurate ECG reports. In recent years, neural network-based automatic ECG diagnosis methods have exhibited promising performance, suggesting a potential alternative to the labor-intensive examination conducted by cardiologists. However, many existing approaches failed to adequately consider the temporal and channel dimensions when assembling features and ignored interpretability. And clinical theory underscores the necessity of prolonged signal observations for diagnosing certain ECG conditions such as tachycardia. Moreover, specific heart diseases manifest primarily through distinct ECG leads represented as channels. In response to these challenges, this paper introduces a novel neural network architecture for ECG classification (diagnosis). The proposed model incorporates Lead Fusing blocks, transformer-XL encoder-based Encoder modules, and hierarchical temporal attentions. Importantly, this classifier operates directly on raw ECG time-series signals rather than cardiac cycles. Signal integration begins with the Lead Fusing blocks, followed by the Encoder modules and hierarchical temporal attentions, enabling the extraction of long-dependent features. Furthermore, we argue that existing convolution-based methods compromise interpretability, while our proposed neural network offers improved clarity in this regard. Experimental evaluation on a comprehensive public dataset confirms the superiority of our classifier over state-of-the-art methods. Moreover, visualizations reveal the enhanced interpretability provided by our approach. Highlights Our model extracts long-dependent features of ECG signals based on the Transformer-XL encoder. The proposed network offers the improved interpretability. Our classifier achieves superior performance over other state-of-the-art methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.646
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.244
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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