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Record W4391019580 · doi:10.1109/jsen.2024.3353190

Plastic Scintillator Dosimetry of Ultrahigh Dose-Rate 200 MeV Electrons at CLEAR

2024· article· en· W4391019580 on OpenAlexafffund
Alexander Hart, Cloé Giguère, Joseph Bateman, Pierre Korysko, Wilfrid Farabolini, Vilde Rieker, Nolan Esplen, R. Corsini, Manjit Dosanjh, Luc Beaulieu, Magdalena Bazalova‐Carter

Bibliographic record

VenueIEEE Sensors Journal · 2024
Typearticle
Languageen
FieldMedicine
TopicRadiation Therapy and Dosimetry
Canadian institutionsUniversité LavalUniversity of Victoria
FundersNatural Sciences and Engineering Research Council of CanadaCanada Research ChairsDiscovery Eye Foundation
KeywordsScintillatorDosimeterDosimetryLinear energy transferPhysicsIonization chamberLinear particle acceleratorElectronNuclear medicineDose profileDose rateFlash (photography)IonizationLinearityRadiochemistryMaterials scienceNuclear physicsRadiationMedical physicsOpticsDetectorChemistryMedicine

Abstract

fetched live from OpenAlex

Very high energy electron (VHEE) beams with energies greater than 100 MeV may be promising candidates for FLASH radiotherapy due to their favourable dose distributions and accessibility of ultrahigh dose-rates (UHDR). Combining VHEE with the normal tissue-sparing FLASH effect of UHDR radiotherapy could improve patient outcomes. The standard dosimeters used for conventional radiotherapy, including ionization chambers and film, have limited application to UHDR radiotherapy due to deficits in dose rate independence and temporal resolution. Plastic scintillator detectors (PSDs) are a potential alternative. PSDs connected to a Medscint Hyperscint RP-100 were used to measure the response to 200 MeV electrons produced by the CERN Linear Electron Accelerator for Research (CLEAR). The dose-response linearity and radiation hardness of PSDs under UHDR VHEE conditions was investigated, using dose rates up to 1.21 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">9</sup> Gy/s. Two scintillators were investigated: a polystyrene-based BCF-12 and a proprietary polyvinyltoluene (PVT)-based material. The BCF-12 probe exhibited linear light output with dose per train from 4.9 to 125.2 Gy, and dose rates up to 1.16 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">9</sup> Gy/s within a single pulse. The output of the PVT-based probe was linear from 3.9 to 59.5 Gy per train, and dose rates up to 9.92 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sup> Gy/s. While output linearity was retained (R <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> > 0.998) after delivering 26.2 and 13.8 kGy to the BCF-12 and PVT-based probe, respectively, the light output was reduced by < 1.5%/kGy. The performance of PSDs in this work suggest they may be useful real-time dosimeters for applications in UHDR VHEE radiotherapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.033
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.276
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2024
Admission routes2
Has abstractyes

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