A new treatment for blown-out myotomy, a diverticulum formed after peroral endoscopic myotomy
Bibliographic record
Abstract
Blown-out myotomy (BOM) is a potential postoperative complication for achalasia patients after both surgical and peroral endoscopic myotomy (POEM). It causes diverticular-like changes and food retention in the lower esophagus due to residual contraction and impaired discharge of esophageal contents. It occurs in 17.8% of patients after POEM and can be symptomatic [ 1 ]; however, no effective treatment for patients with symptomatic BOM has been reported. A 48-year-old man who underwent POEM for esophageal achalasia (Chicago classification type II, straight type, dilation grade 1) developed BOM 5 years after the procedure. Esophagogastroduodenoscopy (EGD) showed retention of food residue and diverticular-like changes in the lower esophagus ([ Fig. 1 ] a ). A newly developed septum was seen in the former myotomy line, just above the esophagogastric junction, and was likely contributing to his symptoms ([ Fig. 1 ] b ). An endoscopic septal myotomy was therefore planned. Fig. 1 Endoscopic images of the diverticulum prior to treatment showing: a retained food residue; b the newly formed septum. A mucosal incision was made in the lower esophagus in the 7-oʼclock position, avoiding the former myotomy line. A submucosal tunnel was created and continued obliquely through the former myotomy line into the stomach. The septum, which was composed of muscle tissue, was exposed during the submucosal tunneling, and septal myotomy was then performed ([ Fig. 2 ]). The wall of the diverticulum was flattened and the entry site was closed ([ Fig. 3 ]; [ Video 1 ]). Fig. 2 Endoscopic images of the blown-out myotomy being treated showing: a the diverticulum formed after peroral endoscopic myotomy; b the exposed muscular layer that serves as the septum on the anal side of the diverticulum; c the myotomy being performed; d the completed myotomy. Fig. 3 Endoscopic images of the appearance after treatment showing: a no food residue; b the flattened wall of the diverticulum. Quality: mobile 360 480 720 Download A new treatment is performed for blown-out myotomy, a diverticulum that forms after peroral endoscopic myotomy.Video 1 There were no adverse events, and the patient was discharged on postoperative day 4, which is standard for patients undergoing POEM at our institution. His symptoms resolved after this treatment. An EGD and barium esophagram were performed 3 months and 1 year after treatment. The EGD showed no food residue, and the barium esophagram demonstrated improved contrast flow. Endoscopic treatment of Zenkerʼs diverticulum via POEM (Z-POEM) has been reported, but this is the first reported use of the strategy on a post-POEM diverticulum [ 2 ]. Given the nomenclature of other endoscopic myotomy procedures, we suggest using “B-POEM” for this therapy (POEM for BOM). We propose B-POEM as a novel treatment for symptomatic BOM. Endoscopy_UCTN_Code_TTT_1AO_2AN Publication History Article published online: 23 January 2024 © 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/). Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".