MétaCan
Menu
Back to cohort
Record W4391247517 · doi:10.1016/j.emcon.2024.100301

Novel insights into the dehalogenation mechanism and ecotoxicity assessment of 6:2 Cl-PFESA from density functional theory calculations

2024· article· en· W4391247517 on OpenAlexaff
Youxin Xu, Chenxi Zhang, Zhe Wang, Bing Chen, Xiaomin Sun, Shuguang Wang, Huifang Tian

Bibliographic record

VenueEmerging contaminants · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicPer- and polyfluoroalkyl substances research
Canadian institutionsMemorial University of Newfoundland
FundersNatural Science Foundation of Shandong ProvinceNational Natural Science Foundation of China
KeywordsPersulfateChemistryDensity functional theoryProtonationEcotoxicityHalogenationSN2 reactionComputational chemistryMedicinal chemistryOrganic chemistryCatalysisIon

Abstract

fetched live from OpenAlex

The electroplating industry is the main source of 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) pollution, which presents risks to human health and the environment. It is therefore crucial to develop effective 6:2 Cl-PFESA degradation techniques. Persulfate oxidation is a potential treatment method for 6:2 Cl-PFESA due to its outstanding oxidative degradability following the generation of the sulfate radical (SO4•−) and hydroxyl radical (•OH). It has proven difficult to acquire a full understanding of the reaction mechanism and formation of intermediate (IM) products through conventional experimental studies because they are costly and time-consuming. Therefore, a theoretical analysis method based on density functional theory (DFT) calculations was applied. The DFT results showed that electron transfer for the degradation of 6:2 Cl-PFESA could be initiated by the protonated sulfate radical (HSO4•, ΔG≠SET = 9.16 kcal/mol), rather than SO4•− (ΔG≠SET = 41.60 kcal/mol). After desulfonation, the reaction underwent stepwise decarboxylation cycles under the action of •OH, leading to the elimination of the CF2 units until there was complete mineralization into HCl, HF, and CO2. Furthermore, the IMs and the end products of 6:2 Cl-PFESA were evaluated using ECOSAR and TEST software. The low bioaccumulation of the short-chain IMs meant that they could be considered safe in terms of ecotoxicity and health effects. This research determined the theoretical and mechanistic basis of the effects of persulfate in the treatment of water containing 6:2 Cl-PFESA, and its structural analogues.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.290
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueEmerging contaminantsSame topicPer- and polyfluoroalkyl substances researchFrench-language works237,207