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Record W4391317423 · doi:10.1093/bjsopen/zrad145

Novel Textbook Outcomes following emergency laparotomy: Delphi exercise

2024· article· en· W4391317423 on OpenAlexfundno aff
David N Naumann, Aneel Bhangu, Adam Brooks, Matthew J. Martin, Bryan A. Cotton, Mansoor Khan, Mark J. Midwinter, Lyndsay Pearce, Douglas M. Bowley, John B. Holcomb, Ewen A. Griffiths, Adam Abu-Abeid, Adam Peckham-Cooper, Adam R. Dyas, Ademola Adeyeye, Agron Dogjani, Alasdair C Y Ball, Albert Wolthuis, Aleksandar Karamarković, Alessio Giordano, Alexander Fuchs, Alexander Julianov, Alexander W. Phillips, Alexander Zimmermann, Alexandros Charalabopoulos, Alexei Birkun, Alexis Rafael Narvaez‐Rojas, Ali Güner, Amelia Davis, András Vereczkei, Andrea Balla, Andrea Celotti, Andrea Romanzi, Andrea Trombetta, Andrew D. Beggs, Andrew Robertson, Andrew Petrosoniak, Andrew Davies, Ángel Ignacio Lledó Becerra, Anthony Loria, Antonio Brillantino, Antonios Athanasiou, Arda Işık, Argyrios Ioannidis, Ariel Santos, Arin Saha, Arturo Vilches‐Moraga, Asad Choudhry, Asuka Tsuchiya, B. Mark Smithers, Bas P. L. Wijnhoven, Barrie Keeler, Belinda De Simone, Rodica Bîrlă, Biswadev Mitra, Boyko Atanasov, Brian D. Badgwell, Brodie Nolan, Byung Hee Kang, Carlos A. Ordóñez, Carlos Augusto Gomes, Carmen Mueller, Caroline E. Reinke, Carter C. Lebares, Catherine J. Hunter, C. Villodre, Cem Emir Güldoğan, Charalampos Seretis, Charles A. Adams, Charles Pilgrim, Chris Varghese, Christian Owoo, Christian S. Meyhoff, Christina Fleming, Christina M. Stuart, C Lewis-Lloyd, Christopher J. McLaughlin, Claire Stevens, Colin A. Graham, Conor Magee, David Saunders, D. Dante Yeh, Daniel L. Chan, Daniel Moritz Felsenreich, Daniel N. Holena, Dauda Bawa, David J. Bowrey, David S. Liu, David S. Chan, Deb Sanjay Nag, Diane N. Haddad, Diletta Corallino, Dimitrios Damaskos, Dimitrios Moris, Dimitriοs Schizas, Dimitris P. Korkolis, Dinesh Bagaria, Dmitry Mikhailovich Adamovich, Douglas A. Colquhoun, Dinesh Singhal, Manjunath Siddaiah‐Subramanya, Rohit Kapoor, Duncan Wyncoll, Duong Van Hai, Ewoud ter Avest, Edoardo Maria Muttillo, Edoardo Picetti, Edward J. Kelly, Efstratia Baili, Eleonora Pinto, Elif Çolak, Elijah Dixon, Elisa Reitano, Emiko Sultana, Emily Mills, Eric J. Ley, Erik Osterman, Evan G. Pivalizza, Evripidis Tokidis, Anne-Cécile Ezanno, Fausto Catena, Federica Pederiva, Federico Coccolini, Felix Nickel, Ferdinando Agresta, Fernando Navarro Tovar, Fikri M. Abu‐Zidan, Filip Brzeszczyński, Michael El Boghdady, Flávio Roberto Takeda, Francesco Fleres, Francesca Pecchini, Francesco Maria Carrano, Francesco Pata, Francesk Mulita, Fredrik Klevebro, Gabriel Rodrigues, Gaetano Gallo, Gaetano Poillucci, Gary Alan Bass, Geeta Aggarwal, Gennaro Perrone, Geoffrey Roberts, Georgios Koukoulis, Georgios Zacharis, Gian Luca Baiocchi, Gianluca Pellino, Giorgio Lisi, Giovanni Dapri, Giuseppe Brisinda, Goran Augustin, Grigorios Christodoulidis, Guglielmo Imbrìaco, Guillaume Ducarme, Kemal Raşa, Peter Hamer, Hans Lederhuber, Haralds Plaudis, Hayaki Uchino, Hazem Beji, Henry J.M. Ferguson, Hugo M L Cohen, Iain H. Wilson, І. А. Кryvoruchko, Ilari Kuitunen, Ilaria Benzoni, Ilenia Merlini, Ilze Ose, Imtiaz Wani, Ines Gockel, Ionuţ Negoi, Irena Gribovskaja‐Rupp, Ivan Tomasi, Iyiade Olaoye, J Cleo Kenington, J. Scott Roth, Jacob Rosenberg, Jacopo Viganò, James M. Williamson, Jan J. De Waele, Jason Smith, Jeffry Nahmias, Jennifer L. Stevens, Jennifer Rickard, Jin Jiun Mah, Job F. Waalwijk, Jonathan B. Yuval, Joonas H. Kauppila, Joseph Cuschieri, Joshua B. Brown, Juan Gómez Rivas, Juliet Emamaullee, Konstantinos Lasithiotakis, Katherine McKenzie, Kazuhide Matsushima, Antti Koivusalo, Max Almond, Lars Konge, Lars Nannestad Jørgensen, Laurent Genser, Lena M. Napolitano, Leo R. Brown, Lewis J. Kaplan, Luca Degrate, Luigi Bonavina, Lynne Moore, Mahir Gachabayov, Mamun David Dornseifer, Mansour Abdulshafea, Marcelo Augusto Fontenelle Ribeiro, Marcello Migliore, Marco Ceresoli, Marco Clementi, Marco Scarpa, Maria Olausson, Mariana R F Sousa, Mario Giuffrida, Mario D’Oria, Mario Pacilli, Martin Czerny, Martin Reichert, Martin Rutegård, Maryam Bahreini, Matthew J. Lee, Matti Tolonen, Matyas Fehervari, Maurizio Rho, Mauro Podda, Maxime Léger, Maximos Frountzas, Meer M. Chisthi, Meghan Lewis, Mélanie Berube, Melissa Oliveira‐Cunha, Max Marsden, Mesut Tez, Micaela Piccoli, Michael Bath, Michael Flanagan, Michael Gottlieb, Michael L. Pearl, Michael Patrick Achiam, Michael Swart, Mika Ukkonen, Miklosh Bala, Mohamed Ebrahim, Mohammed N AlAli, Monica Ortenzi, Montassar Ghalleb, Morten Hylander Møller, Muhammad Rafaih Iqbal, M. Ali, Munir Tarazi, Nicholas Newton, Nader Hanna, Nadia A. Henriksen, Natalie Blencowe, Neil D. Merrett, Neil T. Welch, Nicola Colucci, Nicola de’Angelis, Nicola Latronico, Nicole L. Werner, Niels D. Martin, Nikolaos Machairas, Nikolay Bugaev, Ning Qi Pang, Obinna Obinwa, Panagiotis Kapsampelis, Paola De Nardi, Paolo Vincenzi, Patricio Lamoza Kohan, Philip H. Pucher, P Herrod, Philip Wai Yan CHIU, Pierluigi Marzuillo, Pierpaolo Sileri, Pietro Fransvea, Pradeep H. Navsaria, P Valentin, Roel Bakx, Rachel L. Choron, Rahul Gupta, Rao R. Ivatury, R Moreno Diaz, Rebecca Bradley, Reitano Elisa, René M. Palacios Huatuco, Reza Shahriarirad, Rishi Rattan, Riyad Karmy-Jones, Robert G. Sawyer, Robert J.S. Coelen, Roberto Cirocchi, Rondi B. Gelbard, Roxanna Zakeri, Rui Farinha, Rutger M. Schols, Ryan P. Dumas, Salomone Di Saverio, Samik Kumar Bandyopadhyay, Samir Delibegović, Sean Stevens, Sergio M. Navarro, Shamita Chatterjee, Stamatios Petousis, Stavros Gourgiotis, Stephanie Streit, Suman Baral, Sunaina Tejpal Karna, Susan Moug, Susan Yoong, Suzanne S. Gisbertz, Tareq Kheirbek, Teoh Yuen-Chun Jeremy, Therèse M. Duane, Thomas Korgaard Jensen, Tim Bright, Timothy Craig Hardcastle, Tania Triantafyllou, Vahagn C. Nikolian, Valentina Bianchi, Victor Kong, Vincenzo Trapani, Vishal G. Shelat, Vishnu R. Mani, Vladimir Khokha, Wah Yang, Waleed Al‐Khyatt, Yick Ho Lam, Yu Kijima, Yunfeng Cui, Zane Perkins, Zaza Demetrashvili, Zi Qin Ng

Bibliographic record

VenueBJS Open · 2024
Typearticle
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsnot available
FundersErasmus Universitair Medisch Centrum RotterdamState University of New York Upstate Medical UniversityMedical Center, University of RochesterUniversity of California, San FranciscoUniversità Politecnica delle MarcheWestern Sydney UniversityUniversité de Tunis El ManarPécsi TudományegyetemSjællands UniversitetshospitalNational and Kapodistrian University of AthensUniversity of Texas MD Anderson Cancer CenterTaysUniversitätsspital ZürichUniversité de TunisTexas Tech UniversityUniversidad ICESIUniversità degli Studi dell'AquilaUniversity of Texas Health Science Center at HoustonRigshospitaletUniversité LavalUmeå UniversitetSchool of Medicine and Public Health, University of Wisconsin-MadisonSyracuse UniversityTehran University of Medical Sciences and Health ServicesUniversidad Autónoma de Nuevo LeónKaradeniz Teknik ÜniversitesiHebrew University of JerusalemUniversity of MiamiKing Faisal Specialist Hospital and Research CentreQueen's UniversityHerlev HospitalNottingham University Hospitals NHS TrustAjou Universityİstanbul Medeniyet ÜniversitesiUniversity of NottinghamUniversity of BristolImperial College LondonUniversity of TorontoRoyal College of Surgeons of EnglandStony Brook UniversityMcGovern Medical SchoolLeonard M. Miller School of MedicineUniversity of BernRush UniversityCentre Hospitalier Universitaire de QuébecUniversità degli Studi di BresciaHamad Medical CorporationGentofte HospitalState University of New YorkUniversity of PennsylvaniaUniversità degli Studi di Milano-BicoccaUniversity of Rochester
KeywordsMedicineLaparotomyLikert scaleDelphi methodSepsisGeneral surgeryEmergency medicineSurgeryPsychology

Abstract

fetched live from OpenAlex

BACKGROUND: Textbook outcomes are composite outcome measures that reflect the ideal overall experience for patients. There are many of these in the elective surgery literature but no textbook outcomes have been proposed for patients following emergency laparotomy. The aim was to achieve international consensus amongst experts and patients for the best Textbook Outcomes for non-trauma and trauma emergency laparotomy. METHODS: A modified Delphi exercise was undertaken with three planned rounds to achieve consensus regarding the best Textbook Outcomes based on the category, number and importance (Likert scale of 1-5) of individual outcome measures. There were separate questions for non-trauma and trauma. A patient engagement exercise was undertaken after round 2 to inform the final round. RESULTS: A total of 337 participants from 53 countries participated in all three rounds of the exercise. The final Textbook Outcomes were divided into 'early' and 'longer-term'. For non-trauma patients the proposed early Textbook Outcome was 'Discharged from hospital without serious postoperative complications (Clavien-Dindo ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation or death). For trauma patients it was 'Discharged from hospital without unexpected transfusion after haemostasis, and no serious postoperative complications (adapted Clavien-Dindo for trauma ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation on or death)'. The longer-term Textbook Outcome for both non-trauma and trauma was 'Achieved the early Textbook Outcome, and restoration of baseline quality of life at 1 year'. CONCLUSION: Early and longer-term Textbook Outcomes have been agreed by an international consensus of experts for non-trauma and trauma emergency laparotomy. These now require clinical validation with patient data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.115
metaresearch head score (Gemma)0.142
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.115
Threshold uncertainty score0.610

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1150.142
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0040.004
Scholarly communication0.0040.003
Open science0.0030.013
Research integrity0.0030.005
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.362
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations11
Published2024
Admission routes1
Has abstractyes

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