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Battling the JN.1 Surge: Unveiling strategies to shield against the next wave of COVID with homoeopathy

2024· article· en· W4391724362 on OpenAlexaboutno aff
Pranali Mistry, Briyal Patel, Nayana Patel

Bibliographic record

VenueInternational Journal of Homoeopathic Sciences · 2024
Typearticle
Languageen
FieldMedicine
TopicComplementary and Alternative Medicine Studies
Canadian institutionsnot available
Fundersnot available
KeywordsHomeopathyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)SurgeShieldVirologyMedicineGeographyGeologyMeteorologyAlternative medicineInternal medicine

Abstract

fetched live from OpenAlex

This article delves into the emergence of the JN.1 sub-variant of the Omicron strain, labelled a "variant of interest" by the World Health Organization. Originating from BA.2.86, JN.1 carries the spike protein L455S mutation, raising concerns about its potential to evade vaccine immunity. With a global prevalence of 27.1%, impacting nations like India, Canada, France, Singapore, Sweden, and the UK, JN.1's increased transmissibility and immune evasion potential are highlighted. In India, JN.1 contributes to a surge in cases, notably with lower hospitalization rates. The article explores JN.1's pathophysiology, emphasizing the ACE2 receptor binding impact of the S: L455S mutation. Clinical features from mild to severe cases are detailed, and investigative methods, including genomic sequencing and serological assays, are crucial for understanding and managing JN.1. Despite vaccine resistance, current immunization remains effective against severe outcomes. The article concludes by discussing homoeopathic management, stressing a holistic symptom relief approach, and underscores the importance of collaborative efforts, transparency, and ongoing research to mitigate JN.1's impact and protect global public health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0020.002
Scholarly communication0.0020.003
Open science0.0000.002
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.378
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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