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Record W4391757518 · doi:10.1101/2024.02.12.579950

Enhancement of Temporal Processing via Transcutaneous Vagus Nerve Stimulation

2024· preprint· en· W4391757518 on OpenAlexafffund
Mehrdad Bahadori, Neha Bhutani, Simone Dalla Bella

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldNeuroscience
TopicVagus Nerve Stimulation Research
Canadian institutionsUniversité de MontréalInternational Laboratory for Brain, Music and Sound ResearchCentre for Research on Brain Language and Music
FundersMitacs
KeywordsVagus nerve stimulationVagus nerveStimulationNeurosciencePrefrontal cortexMedicinePsychologyCognition

Abstract

fetched live from OpenAlex

Abstract Background The vagus nerve, a crucial component of the parasympathetic nervous system, serves as a vital communication link between the brain and body. Recent studies indicate that auricular stimulation of the vagus nerve can influence executive functions by increasing activity in brain regions like the prefrontal cortex. While prefrontal areas are associated with temporal processing, it remains unclear whether vagus nerve stimulation can also impact time perception. Hypothesis The stimulation of the vagus nerve via its auricular branch may enhance performance in temporal processing by boosting activities in prefrontal brain areas related to temporal processing. Methods Temporal processing abilities were assessed using an anisochrony detection task, where participants identified temporal irregularities in otherwise isochronous sequences while undergoing transcutaneous Vagus Nerve Stimulation (tVNS) or sham stimulation. Results The results of this study, for the first time, revealed that participants could recognize smaller temporal shifts when the vagus nerve was stimulated, compared to the sham condition. Conclusion The findings suggest that vagus nerve stimulation modulates temporal processing, supporting the notion that transcutaneous stimulation of the vagus nerve can influence cognitive functions related to temporal processing, possibly by enhancing prefrontal activities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.287
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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Same venuebioRxiv (Cold Spring Harbor Laboratory)Same topicVagus Nerve Stimulation ResearchFrench-language works237,207