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Record W4391774362 · doi:10.1016/j.jcjp.2024.100165

Body mass index and sex and their effect on patient-reported outcomes following cartilage repair: an insight from the International Cartilage Regeneration and Joint Preservation Society Patient Registry

2024· article· en· W4391774362 on OpenAlexaff
Gwenllian Tawy, Reza Ojaghi, Michael J. McNicholas

Bibliographic record

VenueJournal of Cartilage & Joint Preservation · 2024
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsBody mass indexCartilageMedicineIndex (typography)Internal medicineComputer scienceAnatomyWorld Wide Web

Abstract

fetched live from OpenAlex

<h2>Abstract</h2><h3>Introduction</h3> Chondral injuries in the knee, whether isolated or accompanying other injuries are found in as many as 60% of arthroscopic examinations. Although current research has identified negative outcomes for patients with a body mass index (BMI) >30kg/m<sup>2</sup> undergoing chondral repair, our understanding of the relationship between presurgery BMI and postoperative patient-reported outcomes across all BMI categories remains lacking. <h3>Objectives</h3> Through the International Cartilage Regeneration and Joint Preservation Society (ICRS) Patient Registry, this study aimed to explore this relationship, taking into account sex variations. <h3>Methods</h3> The ICRS Patient Registry was used to extract the data for this study. The outcomes in focus were the Knee Osteoarthritis Outcome Score (KOOS) and EQ-5D scores. Pearson and Spearman correlation methods were applied and the level of significance was set as <mml:math><mml:mi>α</mml:mi></mml:math>= 0.05. <h3>Results</h3> Of 3194 Registry patients at the time of data extraction, 1757 had undergone a surgical procedure, and 336 of these had complete KOOS or EQ-5D scores available for 6-week, 6-month, and 1-year postoperation. Analyses revealed that neither male (average BMI – 28.2 kg/m<sup>2</sup>) nor female (average BMI – 25.3 kg/m<sup>2</sup>) data sets indicated a correlation between BMI and the patient-reported outcomes. <h3>Conclusions</h3> BMI, irrespective of sex, is not correlated with patient-reported outcomes in patients enrolled in the ICRS Registry with a BMI <30 kg/m<sup>2</sup>. Although BMIs in the overweight classification were not associated with poorer outcomes than BMIs in the normal classification, the current literature continues to support the notion that a BMI >30 kg/m<sup>2</sup> is linked to poor cartilage repair and failure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.868

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.002
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.251
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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