A131 OUTCOMES AND COMPLICATIONS OF THERAPEUTIC ERCP IN DIFFERENT AGE GROUPS
Bibliographic record
Abstract
Abstract Background Endoscopic Retrograde Cholangiopancreatography (ERCP) is a vital procedure for hepatobiliary disease management. Though it boasts high overall success rates, the impact of patient age on outcomes remains uncertain, especially amongst elderly patients. With an aging population, it is crucial to determine the efficacy and safety of ERCP in different age groups. Aims This study assesses ERCP success and complication rates across age groups. Our objective is to investigate whether ERCP remains a reliable and safe procedure for patients of all ages, particularly the elderly. Methods A database with retrospective data from consecutive patients undergoing ERCP at a Canadian tertiary care centre between 2011 and 2020 was utilized. Baseline patient characteristics and indications for ERCP were collected. Outcomes included procedural success, complications, and procedure duration. Patients were categorized into four age groups: ampersand:003C40, 40-65, 65-80, and ampersand:003E80, with a specific sub-analysis for patients ampersand:003C80 and ampersand:003E80. Results This study included 6132 patients. Significant disparities were observed in comorbid conditions (pampersand:003C0.0001), ASA status (pampersand:003C0.0001), and the use of anticoagulants or antiplatelet agents (pampersand:003C0.0001). The most common indications for ERCP were gallstones (45.1%), jaundice (19.2%), and ductal lesions (12.8%), with no significant variation among the age groups (p=0.5983). There was a significant difference in procedural success (p=0.0005), with declining success in older age groups (ampersand:003C40 = 91.3%, 40-65 = 87.4%, 65-80 = 86.2%, ampersand:003E80 = 84.9%), and this difference remained significant in the ampersand:003C80 and ampersand:003E80 sub-analysis (p=0.0133). While mean procedure duration was longer in older age groups (pampersand:003C0.0001), incidence of complications did not vary across all groups (p values [EH1] = 0.1532-0.7622) or patients ampersand:003C80 and ampersand:003E80 (p= 0.0769-0.7128). Conclusions ERCP maintains a high success rate and safety profile across all age groups; however, success rates decline and procedure times increase significantly in older patients. ERCP outcomes across age groups Funding Agencies None
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".