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Record W4392058364 · doi:10.1038/s41467-024-45355-3

Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines

2024· review· en· W4392058364 on OpenAlexaff
Alexander P. L. Martindale, Carrie Llewellyn, Richard de Visser, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden‐Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher Kelly, Cecilia S. Lee, Christopher Yau, An‐Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu

Bibliographic record

VenueNature Communications · 2024
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsWomen's College HospitalUniversity of TorontoHospital for Sick ChildrenPublic Health OntarioGenome CanadaOttawa Hospital
FundersNational Institute for Health and Care ResearchCancer Research UK
KeywordsConsolidated Standards of Reporting TrialsConcordancePsychological interventionMedicineRandomized controlled trialSystematic reviewMEDLINEProtocol (science)Family medicineAlternative medicinePathologyInternal medicine

Abstract

fetched live from OpenAlex

The Consolidated Standards of Reporting Trials extension for Artificial Intelligence interventions (CONSORT-AI) was published in September 2020. Since its publication, several randomised controlled trials (RCTs) of AI interventions have been published but their completeness and transparency of reporting is unknown. This systematic review assesses the completeness of reporting of AI RCTs following publication of CONSORT-AI and provides a comprehensive summary of RCTs published in recent years. 65 RCTs were identified, mostly conducted in China (37%) and USA (18%). Median concordance with CONSORT-AI reporting was 90% (IQR 77-94%), although only 10 RCTs explicitly reported its use. Several items were consistently under-reported, including algorithm version, accessibility of the AI intervention or code, and references to a study protocol. Only 3 of 52 included journals explicitly endorsed or mandated CONSORT-AI. Despite a generally high concordance amongst recent AI RCTs, some AI-specific considerations remain systematically poorly reported. Further encouragement of CONSORT-AI adoption by journals and funders may enable more complete adoption of the full CONSORT-AI guidelines.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.635
metaresearch head score (Gemma)0.787
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.365
Threshold uncertainty score0.450

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.6350.787
Meta-epidemiology (narrow)0.0050.006
Meta-epidemiology (broad)0.0190.033
Bibliometrics0.0190.022
Science and technology studies0.0050.009
Scholarly communication0.0140.008
Open science0.0100.008
Research integrity0.0140.015
Insufficient payload (model declined to judge)0.0140.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.733
GPT teacher head0.640
Teacher spread0.093 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSystematic review
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations40
Published2024
Admission routes1
Has abstractyes

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Same venueNature CommunicationsSame topicArtificial Intelligence in Healthcare and EducationFrench-language works237,207