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Record W4392157536 · doi:10.21203/rs.3.rs-3835786/v1

Enhancing Upper Extremity Muscle Strength in Individuals with Spinal Cord Injury Using Low-Intensity Blood Flow Restriction Exercise

2024· preprint· en· W4392157536 on OpenAlexafffundabout
Babak Shadgan, Mehdi Nouri Zadeh, Yekta Saremi, Leila Baktash, Stefan Lazarevic

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsUniversity of British Columbia
FundersInternational Collaboration on Repair DiscoveriesMichael Smith Health Research BC
KeywordsBlood flow restrictionSpinal cord injuryIntensity (physics)Physical medicine and rehabilitationMedicineBlood flowMuscle strengthPhysical therapySpinal cordInternal medicineResistance trainingPhysics

Abstract

fetched live from OpenAlex

Abstract Study Design A randomized experimental design. Objectives This study explores the feasibility and effects of low-intensity blood flow restriction (LI-BFR) exercise on forearm muscle strength and function in individuals with spinal cord injury (SCI). Setting International Collaboration on Repair Discoveries, Vancouver, Canada. Methods Ten male and female participants with SCI, aged 18-75, underwent an 8-week LI-BFR exercise program that targeted forearm muscles. Grip strength was the primary outcome measure, and participants also provided qualitative feedback on their experiences. Results The study revealed a significant increase in forearm muscle strength among participants in the intervention group who engaged in LI-BFR training, with an average strength gain of 7.5 ± 0.37 kg post 16 exercise sessions (Cohen`s d=-6.32, 95% CI: -8.34, -6.68). In contrast, the control group, following a conventional high-intensity exercise regimen without BFR, showed a more modest strength increase of 4.4 ± 0.68 kg. Additionally, the intervention was well-received, with minimal reported discomfort and high participant satisfaction. A mean Patient's Global Impression of Change (PGIC) score of 2.2 reflected overall improvements in participants' daily activities and health status. Conclusions This study highlights the feasibility and efficacy of LI-BFR exercise as a safe method to improve forearm muscle strength in individuals with SCI. The extension of this technique to target additional limb muscles holds promise for advancing muscle rehabilitation in the SCI population. The positive outcomes and high level of participant satisfaction suggest that this innovative method can enhance functional independence and elevate the overall quality of life of this population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.038

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.004
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0110.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.386
Teacher spread0.340 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes3
Has abstractyes

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