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Record W4392365647 · doi:10.1093/jalm/jfad122

Serum Free Light Chain and Drift: Calibrator Adjustment Needed?

2024· letter· en· W4392365647 on OpenAlexaffabout
Mark D. Griffiths, Randal Schneider, Vathany Kulasingam

Bibliographic record

VenueThe Journal of Applied Laboratory Medicine · 2024
Typeletter
Languageen
FieldMedicine
TopicClinical Laboratory Practices and Quality Control
Canadian institutionsUniversity of TorontoUniversity Health Network
FundersAbbott Diagnostics
KeywordsLibrary scienceSociologyMedicineComputer science

Abstract

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Journal Article Serum Free Light Chain and Drift: Calibrator Adjustment Needed? Get access Mark Griffiths, Mark Griffiths Diazyme Laboratories, Inc., Poway, CA, United States Search for other works by this author on: Oxford Academic Google Scholar Randal J Schneider, Randal J Schneider Abbott Laboratories, Abbott Park, IL, United States Search for other works by this author on: Oxford Academic Google Scholar Vathany Kulasingam Vathany Kulasingam Division of Clinical Biochemistry, University Health Network, Toronto, ON, CanadaDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada Address correspondence to this author at: Clinical Biochemistry, Toronto General Hospital, 200 Elizabeth St. Rm 3EB-362D, Toronto, Ontario M5G 2C4, Canada. E-mail vathany.kulasingam@uhn.ca. Search for other works by this author on: Oxford Academic Google Scholar The Journal of Applied Laboratory Medicine, Volume 9, Issue 2, March 2024, Pages 394–396, https://doi.org/10.1093/jalm/jfad122 Published: 01 March 2024

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.034
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.007
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.299
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2024
Admission routes2
Has abstractyes

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