HEPATITE MEDICAMENTOSA POR CERTOLIZUMABE PEGOL EM PACIENTE COM DOENÇA DE CROHN: RELATO DE CASO
Bibliographic record
Abstract
Apresentação do Caso Um paciente do sexo masculino, de 31 anos, com doença de Crohn (DC), Montreal A2L3B2 (diagnóstico aos 24 anos), teve tuberculose latente tratada e tratamento convencional com corticosteroide e azatioprina em outro serviço. Em função da intratabilidade clínica, necessitou de ileocolectomia segmentar aos 30 anos, com ressecção de 130 cm de íleo e ileostomia terminal. Para a terapia de manutenção no PO, optou-se por certolizumabe pegol. Após a sexta dose de manutenção, estabeleceu-se o diagnóstico de hepatite medicamentosa por meio de exames laboratoriais. A conduta então foi a suspensão da terapia biológica e manutenção da corticoterapia.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.022 | 0.011 |
| Meta-epidemiology (narrow) | 0.000 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".