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Record W4392816522 · doi:10.1101/2024.03.12.24303708

The association between delirium and falls in older adults in the community: a systematic review

2024· review· en· W4392816522 on OpenAlexaboutno aff
Charlotte Eost‐Telling, Lucy McNally, Yang Yang, Chunhu Shi, Gill Norman, Saima Ahmed, Brenda Agyeiwaa Poku, Annemarie Money, Helen Hawley-Hague, Chris Todd, Susan D. Shenkin, Emma Vardy

Bibliographic record

VenuemedRxiv · 2024
Typereview
Languageen
FieldMedicine
TopicIntensive Care Unit Cognitive Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsDeliriumPsycINFOCINAHLMedicineMEDLINEMeta-analysisSystematic reviewSubgroup analysisPublication biasAssociation (psychology)Cochrane LibraryPsychiatryPsychologyInternal medicinePsychological intervention

Abstract

fetched live from OpenAlex

ABSTRACT Objective Systematically review and critically appraise evidence for the association between delirium and falls in community-dwelling adults aged 60 years and above Methods We searched EMBASE, MEDLINE, PsycINFO, Cochrane Database of Systematic Reviews, CINAHL and Evidence-Based Medicine Reviews (EBMR) databases in April 2023. Standard methods were used to screen, extract data, assess risk of bias (using Newcastle Ottawa scale), provide a narrative synthesis and where appropriate conduct meta-analysis. Results We included eight studies, with at least 3505 unique participants. Five found limited evidence for an association between delirium and subsequent falls: one adjusted study showed an increase in falls (RR 6.66;95% CI 2.16-20.53) but the evidence was low certainty. Four non-adjusted studies found no clear effect. Three studies (one with two subgroups treated separately) found some evidence for an association between falls and subsequent delirium: meta-analysis of three adjusted studies showed an increase in delirium (pooled OR 2.01; 95%CI 1.52-2.66), one subgroup of non-adjusted data found no clear effect. Number of falls and fallers were reported in the studies. Four studies and one subgroup were at high risk of bias and one study had some concerns. Conclusions We found limited evidence for the association between delirium and falls. More methodologically rigorous research is needed to understand the complex relationship, establish how and why this operates bi-directionally and identify potential modifying factors involved. We recommend the use of standardised assessment measures for delirium and falls. Clinicians should be aware of the potential relationship between these common presentations. Key points This is the first systematic review of the association between delirium and falls in the wider community population. There is relatively limited but consistent evidence on the direction of effect for both delirium preceding falls and falls preceding delirium. More high-quality longitudinal work is needed to explore the nature of this potentially complex and bidirectional relationship. History of falls and delirium should be considered when assessing patients with incidence/suspected incidence of falls or delirium.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.022
metaresearch head score (Gemma)0.104
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.022
Threshold uncertainty score0.114

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0220.104
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0130.009
Bibliometrics0.0130.010
Science and technology studies0.0010.002
Scholarly communication0.0040.004
Open science0.0020.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.341
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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