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Record W4393282102 · doi:10.1016/j.kint.2024.03.011

Evidence from the large VALIGA cohort validates the subclassification of focal segmental glomerulosclerosis in IgA nephropathy

2024· article· en· W4393282102 on OpenAlexaff
Shubha S. Bellur, Stéphan Troyanov, Olga Vorobyeva, Rosanna Coppo, Ian S D Roberts, J. Feehaly, S. Troyanov, Daniel C. Cattran, H. Terence Cook, Ian S.D. Roberts, John Scott Radcliffe, María Luisa Russo, Vladimı́r Tesař, Dita Maixnerová, Sigrid Lundberg, Loreto Gesualdo, Francesco Emma, Laura Fuiano, G. Beltrame, Cristiana Rollino, A Amore, Roberta Camilla, Licia Peruzzi, Manuel Praga, Sandro Feriozzi, Rosaria Polci, Giuseppe Segoloni, Loredana Colla, Antonello Pani, Doloretta Piras, Andrea Angioi, G. Cancarini, S. Ravera, Magdalena Durlik, Elisabetta Moggia, José Ballarín, S. Di Giulio, Francesco Pugliese, I. Serriello, Mehmet Şükrü Sever, İşın Kiliçaslan, Francesco Locatelli, Lucia Del Vecchio, Jack F.M. Wetzels, Harm Peters, U. Berg, Fernanda Carvalho, A.C. da Costa Ferreira, M. Maggio, Andrzej Więcek, Mai Ots-Rosenberg, Riccardo Magistroni, Rezan Topaloğlu, Yelda Bilginer, Marco DʼAmico, Katerina Papagianni, Μaria Stangou, F Giacchino, Dimitrios Goumenos, M. Papasotirious, Pantelitsa Kalliakmani, Miltiadis Gerolymos, Kres̆imir Gales̃ić, Luka Torić, Colin Geddes, Kostas C. Siamopoulos, Olga Balafa, Marco Galliani, Piero Stratta, Marco Quaglia, R Bergia, Raffaella Cravero, Maurizio Salvadori, Lino Cirami, Bengt Fellström, Hilde Kloster Smerud, Franco Ferrario, T. Stellato, Jesús Egido, Carina Aguilar Martín, J. Floege, Frank Eitner, Antonio Lupo, Patrizia Bernich, Paolo Mené, Massimo Morosetti, Cees van Kooten, Ton J. Rabelink, Marlies E. J. Reinders, J.M. Boria Grinyo, Stefano Cusinato, Luisa Benozzi, Silvana Savoldi, C. Licata, Małgorzata Mizerska-Wasiak, Maria Roszkowska–Blaim, Tomasz Hryszko, Marian Klinger, Dorota Kamińska, Magdalena Krajewska, G Martina, A Messuerotti, Antonio Dal Canton, Ciro Esposito, C. Migotto, G Triolo, Filippo Mariano, Claudio Pozzi, R Boero, Alexandra Cambier, Gianna Mazzucco, C. Giannakakis, Eva Honsová, B. Sundelin, Anna Maria Di Palma, F. Diomedi-Casadei, Ester Gutiérrez, A.M. Asunis, Jonathan Barratt, Regina Tardanico, Agnieszka Perkowska‐Ptasińska, J. Arce Terroba, M. Fortunato, Afroditi Pantzaki, E. J. Steenbergen, M. Soderberg, Živile Riispere, Luciana Furci, Dıclehan Orhan, David Kipgen, Donatella Casartelli, Danica Galešić Ljubanović, Hariklia Gakiopoulou, E. Bertoni, P. Cannata Ortiz, Henryk Karkoszka, Hermann-Josef Groene, Antonella Stoppacciaro, Ingeborg M. Bajema, J Bruijn, Jadwiga Małdyk, E. Ioachim, Virginie Royal

Bibliographic record

VenueKidney International · 2024
Typearticle
Languageen
FieldMedicine
TopicRenal Diseases and Glomerulopathies
Canadian institutionsUniversité de MontréalHôpital du Sacré-Cœur de MontréalWilliam Osler Health SystemQueen's University
FundersEuropean Renal Association-European Dialysis and Transplant Association
KeywordsFocal segmental glomerulosclerosisMedicineNephropathyGlomerulosclerosisCohortInternal medicineGlomerulonephritisProteinuriaKidneyEndocrinology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.037

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.017
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0030.001
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.299
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2024
Admission routes1
Has abstractno

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