MétaCan
Menu
Back to cohort
Record W4393843868 · doi:10.5281/zenodo.10535021

HAPPY: a deep learning pipeline for mapping cell-to-tissue graphs across placenta histology whole slide images

2024· dataset· en· W4393843868 on OpenAlexaff
Claudia Vanea, Jelisaveta Džigurski, Valentina Rukins, Omri Dodi, Siim Siigur, Liis Salumäe, Karen Meir, W. Tony Parks, Drorith Hochner‐Celnikier, Abigail Fraser, Hagit Hochner, Triin Laisk, Linda M. Ernst, Cecilia M. Lindgren, Christoffer Nellåker

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2024
Typedataset
Languageen
FieldComputer Science
TopicAI in cancer detection
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsPipeline (software)HistologyPlacentaComputer scienceArtificial intelligenceBiologyPathologyMedicinePregnancyFetus

Abstract

fetched live from OpenAlex

These two zipped folders contain all data necessary to train, validate and reproduce results from the paper. Unzipping the files will create 6 folders. Data from folders with the same name across both zips should be combined into one folder. The 'annotations' folder contains all ground truth annotations for training all three deep learning models. The 'datasets' folder contains images for training the nuclei localisation and cell classification models. The 'embeddings' folder contains cell embedding vectors and nuclei coordinates from two slides used to create nodes to train the graph tissue classification model. The 'graph_splits' folder contains regions defining the validation and test splits for the graph model. The 'slides' folder contains a sample region of a whole slide image as a .tiff file for running the inference demo. The 'trained_models' folder contains trained weights for each of the three models. Further instructions for dataset use and creation of custom datasets are available in the GitHub readme: https://github.com/Nellaker-group/happy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.039
Threshold uncertainty score0.129

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0030.002
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0030.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0390.046

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.274
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueZenodo (CERN European Organization for Nuclear Research)Same topicAI in cancer detectionFrench-language works237,207