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Record W4394463658 · doi:10.6084/m9.figshare.21213431

Additional file 2 of Whole-genome sequencing reveals the genetic mechanisms of domestication in classical inbred mice

2022· dataset· en· W4394463658 on OpenAlexaff
Ming Liu, Caixia Yu, Zhichao Zhang, Mingjing Song, Xiuping Sun, Jaroslav Piálek, Jens Jacob, Jiqi Lu, Lin Cong, Hongmao Zhang, Yong Wang, Guoliang Li, Zhiyong Feng, Zhenglin Du, Meng Wang, Xinru Wan, Dawei Wang, Yanling Wang, Hongjun Li, Zuoxin Wang, Bing Zhang, Zhibin Zhang

Bibliographic record

VenueOpen MIND · 2022
Typedataset
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAnimal Genetics and Reproduction
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsDomesticationBiologyGeneticsGenomeInbred strainWhole genome sequencingDNA sequencingEvolutionary biologyComputational biologyDNAGene

Abstract

fetched live from OpenAlex

Additional file 2: Table S7. Genes located in low nucleotide diversity regions (top 5%) in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S8. Functional categories of the genes (p < 0.05) located at low nucleotide diversity regions (top 5%) in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S9. Genes located in top 5% Fst regions in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S10. Functional categories of the genes (p < 0.05) located in top 5% Fst regions in classical inbred mice strains compared to wild and wild-derived inbred mice. Table S11. Genes with top 5% XP-CLR score in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S12. Functional categories of the genes (p < 0.05) with top 5% XP-CLR score in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S13. Common 339 positively selected genes (PSGs) in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S14. Functional categories of the common 339 positively selected genes in classical inbred mice strains as compared to wild and wild-derived inbred mice. Table S15. Common 355 positively selected genes between classical inbred mice strains and wild mice after excluding wild-derived inbred mice. Table S16. Genes significantly higher expressed in immature brain/brain than in other tissues. Table S17. Abnormal phenotypes of the 245 genes from 339 PSGs reported in mouse models. Table S18. Differently expressed genes of the 339 PSGs in the hippocampus between classical inbred and wild mice. Table S19. Differently expressed genes of the 339 PSGs in the frontal lobe between classical inbred and wild mice. Table S20. Differently expressed genes of the 339 PSGs in the hypothalamus between classical inbred and wild mice. Table S22. Selected sites with reference allele homozygous not existing in any wild mice, but existing in all the classical inbred mice. Table S24. SNPs located in Astn2 gene with no homozygous of reference allele in wild mice. Table S25. SNPs located in Astn2 gene with high selective potential.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.480
Threshold uncertainty score0.521

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.4800.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.270
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractyes

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Same venueOpen MINDSame topicAnimal Genetics and ReproductionFrench-language works237,207