MétaCan
Menu
Back to cohort
Record W4394682640 · doi:10.1016/j.cjco.2024.03.015

An Innovative Patient-Centred Approach to Heart Failure Management: The Best Care Heart Failure Integrated Disease-Management Program

2024· article· en· W4394682640 on OpenAlexaff
Christopher Licskai, A. J. Hussey, Madonna Ferrone, Melissa Fisk, Shanil Narayan, Tim O’Callahan, Andrew Scarffe, Shannon L. Sibbald, Dhssraj Singh, Teresa To, Jari M. Tuomi, Robert S. McKelvie

Bibliographic record

VenueCJC Open · 2024
Typearticle
Languageen
FieldMedicine
TopicHeart Failure Treatment and Management
Canadian institutionsThunder Bay Regional Health Sciences CentreInstitute for Clinical Evaluative SciencesPublic Health OntarioHospital for Sick ChildrenUniversity of OttawaSt Joseph's Health CareUniversity of TorontoHôtel-Dieu Grace HealthcareLondon Health Sciences CentreWestern University
FundersPfizer
KeywordsHeart failureDisease managementMedicineIntensive care medicineDiseaseManagement of heart failureCardiologyInternal medicine

Abstract

fetched live from OpenAlex

BackgroundThe management of heart failure (HF) is challenging because of the complexities in recommended therapies. Integrated disease management (IDM) is an effective model, promoting guideline directed care, however, the impact of IDM in the community setting requires further evaluation.MethodsA retrospective evaluation of community-based IDM. Patient characteristics were described, and evaluation of outcomes using a pre- and post-intervention design were HF-related health service use, quality of life, and concordance with guideline-directed medical therapy (GDMT).Results715 patients were treated in the program (2016 to 2023), 219 in a community specialist clinic and 496 in 25 primary care clinics. The overall cohort was predominantly male (60%), mean age of 73.5 years (±10.7), and 60% with HF reduced ejection fraction.In patients with ≥6 months of follow-up (N=267), pre vs post annualized rates of HF-related acute health services decreased from 36.3 to 8.5 hospitalizations/100 patients/year, p<0.0001, 31.8 to 13.1 ED visits/100 patients/year, p<0.0001, and 152.8 to 110.0 urgent physician visits/100 patients/year, p=0.0001. GDMT improved; patients receiving triple therapy and quadruple therapy increased by 10.1% (95%CI;2.4%,17.8%) and 19.6% (95%CI;12.0%,27.3%), respectively. Within these groups optimal dosing was achieved in 42.5% (95%CI;32.0%,53.6%) and 35.0% (95%CI;23.1%,48.4%), respectively. In patients with at least one follow-up (N=286) over 50% experienced a clinically relevant improvement in quality of life.ConclusionA community-based IDM program for HF, may reduce HF-related acute health service use, improve quality of life and GDMT. These encouraging preliminary outcomes from a real-world program evaluation require confirmation in a randomized controlled trial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.751
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.301
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueCJC OpenSame topicHeart Failure Treatment and ManagementFrench-language works237,207