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Record W4394860521 · doi:10.24911/biomedica/5-1135

Turmeric Gel as alternative Non-Vital Pulpotomy medicament in Primary teeth- A Randomized Controlled Trial

2024· article· en· W4394860521 on OpenAlexaff
Mashal Mazhar, Shazia Naz, Ambreen Zahra, Nazia Bashir, Rabia Dastgeer

Bibliographic record

VenueBIOMEDICA · 2024
Typearticle
Languageen
FieldDentistry
TopicEndodontics and Root Canal Treatments
Canadian institutionsCollège Montmorency
FundersUniversity of Health Sciences Lahore
KeywordsPulpotomyMedicineRandomized controlled trialDentistrySurgeryMolar

Abstract

fetched live from OpenAlex

<p><strong>Background and objective: </strong>Formocresol is a gold standard medicament in both vital and non-vital Pulpotomies due to its potent antibacterial potential but, it has a controversial nature due to its side effects. Therefore, the demand for natural alternatives of Formocresol as a pulp dressing material, with few or no side effects, became imperative. The purpose of the study was to introduce Turmeric gel as non-vital Pulpotomy medicament in primary teeth by evaluating its antibacterial effect against<em> Streptococcus mutans</em> and <em>Lactobacillus acidophilus</em>.</p> <p><strong>Method: </strong>It was a multi-arm parallel Randomized Controlled Trial in which sixty patients aged between 4 to 8 years, each containing at-least one non-vital primary molar, were selected and randomly divided into Group A (Formocresol) and Group B (Turmeric gel). Non-vital Pulpotomy was performed by removing the coronal necrotic pulp. Sterile paper points were dipped in the root canals and taken to the laboratory. Cotton pellets soaked in the respective medicaments were placed over the root canal orifices and filled temporarily. Patients were recalled after one week. Samples were again taken, and tooth restored. Comparison between bacterial count at baseline and after one week of treatment was made and expressed as Colony-Forming Units/ml (CFU/ml).</p> <p><strong>Results:</strong> There was a significant reduction in median <em>Streptococcus mutans</em> and <em>Lactobacillus acidophilus</em> bacterial count in each group after one week of treatment (p < 0.001). Formocresol showed higher average reduction than Turmeric gel. However, statistically, the difference was insignificant indicating that both the medicaments possessed comparable antibacterial effect.</p> <p><strong>Conclusion:</strong> Turmeric gel was found as effective alternative to Formocresol.</p> <p><strong>Randomized Controlled Trial registration number in ClinicalTrials.gov:</strong> NCT05801354</p> <p> </p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.131
Threshold uncertainty score0.961

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.294
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

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